2. Gene
  3. CEBPD - CCAAT enhancer binding protein delta Gene

CEBPD - CCAAT enhancer binding protein delta Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CELF; CRP3; C/EBP-delta; NF-IL6-beta

Gene ID: 1052 | Gene type: protein coding

About CEBPD

Cytogenetic location: 8q11.21 Genomic coordinates (GRCh38): 8:47,736,913-47,738,164 (from NCBI)

This gene has 1 transcript (splice variant), 158 orthologues and 4 paralogues.

Summary

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]

CEBPD Products(1)

mRNA Protein Name
NM_005195.4 NP_005186.2 CCAAT/enhancer-binding protein delta
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20102225 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Cellular Component GO Annotation Evidence Reference Source
part of RNA polymerase II transcription regulator complex IPI
IPI: Inferred from physical interaction
20102225 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CEBPD Protein Structure

bZIP_2

bZIP_2: Basic region leucine zipper (191 - 242)

  • 0
  • 100
  • 200
  • 269 a.a.
Protein Preferred Names Protein Names

CCAAT/enhancer-binding protein delta

CCAAT/enhancer binding protein (C/EBP), delta

CEBPD Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CEBPD P49716 CEBPA Homo sapiens P49715
Peptide Array
20102225
Intra
CEBPD P49716 FANCD2 Homo sapiens Q9BXW9
Anti Tag CoIP
20805509
Intra
CEBPD P49716 FANCD2 Homo sapiens Q9BXW9
Anti Bait CoIP
20805509
Intra
CEBPD P49716 IPO4 Homo sapiens Q8TEX9
Anti Tag CoIP
20805509
Intra
CEBPD P49716 IPO4 Homo sapiens Q8TEX9
Anti Bait CoIP
20805509
Intra
CEBPD P49716 CEBPG Homo sapiens P53567
Peptide Array
20102225
Intra
CEBPD P49716 DDIT3 Homo sapiens P35638
Peptide Array
20102225
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CEBPD Proteins

Cat. No. Product Name Accession Purity
HY-P72134 CEBP delta/CEBPD Protein, Human (His-Myc) P49716 (S2-R269) ≥95%

Related Diseases

Diseases Alias
Speech And Communication Disorders

Language Disorder

Communication Disorder

Language Disorders

Communication Disorders

Speech Language Disorder

Speech-Language Disorder

Communication Impairment

Speech And Language Disorder
Developmental Coordination Disorder

Motor Skills Disorders
Expressive Language Disorder

Developmental Expressive Language Disorder
Specific Language Impairment

Language Impairment, Specific
Mixed Receptive-Expressive Language Disorder
Myotonic Disease

Myotonic Disorders

Myotonic Syndrome

Symptomatic Myotonia
Reading Disorder

Specific Reading Disorder

Reading

Dyslexia

Developmental Reading Disorder
Dysgraphia

Agraphia
Learning Disability

Learning Disabilities

Learning Disorders

Academic Skill Disorder

Learning Disorder
Articulation Disorder

Phonological Disorder

Articulation Disorders

Articulation Impairment

Speech Sound Disorders
Speech Disorder

Speech Disorders
Myotonic Dystrophy 1

Myotonic Dystrophy

Dystrophia Myotonica

Steinert Disease

Myotonic Dystrophy Type 1

Myotonia Atrophica

DM1

Congenital Myotonic Dystrophy

Myotonia Dystrophica

Steinert Myotonic Dystrophy

Dystrophia Myotonica 1

Dm

Steinert'S Disease

Steinert Myotonic Dystrophy Syndrome

Myotonic Dystrophy Of Steinert

Dystrophia Myotonica Type 1

Myotonic Dystrophy Congenital

Dystrophy, Myotonic, Type 1

Dm - [Dystrophia Myotonica]

Myotonic Muscular Dystrophy
Echolalia
Spinocerebellar Ataxia 8

Spinocerebellar Ataxia Type 8

SCA8

Ataxia, Spinocerebellar, Type 8
Dyslexia
Stuttering

Stammering

Familial Persistent Stuttering

Stuttering, Familial Persistent 1
Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity
Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02447 CEBPD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CEBPD VGNC VGNC:106685
Rattus norvegicus CEBPD RGD RGD:2328
Mus musculus CEBPD MGD MGI:103573
Macaca mulatta CEBPD VGNC VGNC:83988
Others CEBPD NCBI