CEACAM7 - CEA cell adhesion molecule 7 Gene

Homo sapiens

Also known as CGM2

Gene ID: 1087 | Gene type: protein coding

About CEACAM7

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,673,303-41,688,270 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 569 orthologues and 24 paralogues. Restricted expression toward colon (RPKM 448.6).

Summary

This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal Cancer. Additionally, lower expression levels of this gene may be predictive of rectal Cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

CEACAM7 Products(2)

mRNA	Protein	Name
NM_001291485.2	NP_001278414.1	carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein
NM_006890.5	NP_008821.2	carcinoembryonic antigen-related cell adhesion molecule 7 preproprotein

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	10436421	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CEACAM7 Protein Structure

V-set

Ig_2

0
100
200
265 a.a.

Protein Preferred Names

Protein Names

carcinoembryonic antigen-related cell adhesion molecule 7

carcinoembryonic antigen CGM2

Recombinant CEACAM7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7825	CEACAM7 Protein, Human (HEK293, His)	AAI21133.1 (T36-F142)	≥95%
HY-P72132	CEACAM7 Protein, Human (His-SUMO)	Q14002 (T36-S242)	≥95%

Related Diseases

Diseases

Alias

Mucinous Cystadenocarcinoma

Cystadenocarcinoma, Mucinous	Pseudomucinous Cystadenocarcinoma
Cystadenocarcinoma Mucinous

Gastrointestinal Carcinoma

Gastrointestinal Neoplasms

Adenosquamous Carcinoma

Adenosquamous Cell Carcinoma	Mixed Adenocarcinoma And Squamous Carcinoma
Carcinoma Adenosquamous	Carcinoma, Adenosquamous

Cervical Adenocarcinoma

Adenocarcinoma Cervix Uteri	Adenocarcinoma Of Cervix
Adenocarcinoma Of The Uterine Cervix	Adenocarcinoma Of The Cervix Uteri

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Goblet Cell Carcinoid

Gcc	Goblet Cell Adenocarcinoid
Goblet Cell Carcinoma	Goblet Cell Tumor
Mucinous Carcinoid	Carcinoid Goblet Cell
Carcinoid, Goblet Cell

Rectum Cancer

Malignant Neoplasm Of Rectum	Rectal Cancer
Cancer Of Rectum	Carcinoma Of Rectum
Carcinoma Of The Rectum	Malignant Rectal Tumor
Malignant Rectum Tumor	Malignant Tumor Of Rectum
Rectal Carcinoma	Rectal Cancers
Cancer, Rectal

Ovarian Cyst

Ovarian Cysts

Paget Disease, Extramammary

Extramammary Paget Disease	Cutaneous Paget'S Disease
Extramammary Paget'S Disease	Paget Disease Extramammary
Cutaneous Paget Disease	Paget'S Disease Of Skin
Empd	Extramammary Pagets Disease

Pleural Tuberculosis

Pearly Disease	Tuberculosis Of Pleura
Tuberculous Pleurisy	Tuberculous Pleurisy In Primary Progressive Tuberculosis
Tuberculous Pleuritis	Pleurisy Tuberculous
Tuberculosis, Pleural	Serosal Tuberculosis Of Cattle

Colon Adenocarcinoma

Adenocarcinoma Of Colon	Adenocarcinoma Of The Colon
Colonic Adenocarcinoma

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Lung Cancer Susceptibility 3

Lung Adenocarcinoma	Adenocarcinoma Of Lung
LNCR3	Adenocarcinoma Of Lung, Susceptibility To
Bronchogenic Lung Adenocarcinoma	Nonsmall Cell Adenocarcinoma
Adenocarcinoma Lung	Lung Adenocarcinomas
Non-Small Cell Adenocarcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02443	CEACAM7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CEACAM7	VGNC	VGNC:109596
Others	CEACAM7	NCBI

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