2. Gene
  3. PNRC1 - proline rich nuclear receptor coactivator 1 Gene

PNRC1 - proline rich nuclear receptor coactivator 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as B4-2; PRR2; PROL2; PNAS-145

Gene ID: 10957 | Gene type: protein coding

About PNRC1

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,080,751-89,085,160 (from NCBI)

This gene has 3 transcripts (splice variants), 176 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 61.8), adrenal (RPKM 44.5) and 25 other tissues.

Summary

Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PNRC1 Products(1)

mRNA Protein Name
NM_006813.3 NP_006804.1 proline-rich nuclear receptor coactivator 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17612402 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PNRC1 Protein Structure

PNRC

PNRC: Proline-rich nuclear receptor coactivator motif (276 - 326)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
Protein Preferred Names Protein Names

proline-rich nuclear receptor coactivator 1

proline rich 2 protein

PNRC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
PNRC1 Q12796 POLR3F Homo sapiens Q9H1D9
Anti Tag CoIP
17612402
Intra
PNRC1 Q12796 POLR3F Homo sapiens Q9H1D9
Y2H
17612402
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Uremic Neuropathy
Brachydactyly, Type E2

Brachydactyly Type E2

BDE2

Brachydactyly E2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10802 PNRC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PNRC1 VGNC VGNC:102485
Canis familiaris PNRC1 VGNC VGNC:44761
Bos taurus PNRC1 VGNC VGNC:33098
Macaca mulatta PNRC1 VGNC VGNC:76045
Rattus norvegicus PNRC1 RGD RGD:628753
Mus musculus PNRC1 MGD MGI:1917838