EBNA1BP2 - EBNA1 binding protein 2 Gene

Homo sapiens

Also known as P40; EBP2; NOBP

Gene ID: 10969 | Gene type: protein coding

About EBNA1BP2

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:43,164,174-43,172,570 (from NCBI)

This gene has 9 transcripts (splice variants) and 213 orthologues. Ubiquitous expression in testis (RPKM 24.1), thyroid (RPKM 21.0) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in rRNA processing and ribosomal large subunit biogenesis. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

EBNA1BP2 Products(2)

mRNA	Protein	Name
NM_001159936.1	NP_001153408.1	probable rRNA-processing protein EBP2 isoform 1
NM_006824.3	NP_006815.2	probable rRNA-processing protein EBP2 isoform 2

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleolus	IDA IDA: Inferred from direct assay	2879624	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EBNA1BP2 Protein Structure

Ebp2

0
100
200
306 a.a.

Protein Preferred Names

Protein Names

probable rRNA-processing protein EBP2

nuclear FGF3 binding protein

EBNA1BP2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	EBNA1BP2	Q99848	BRIX1	Homo sapiens	Q8TDN6	Y2H Prey Pooling	32296183
Intra	EBNA1BP2	Q99848	BRIX1	Homo sapiens	Q8TDN6	Anti Tag CoIP	35271311
Intra	EBNA1BP2	Q99848	BRIX1	Homo sapiens	Q8TDN6	Anti Tag CoIP	33961781
Intra	EBNA1BP2	Q99848	BRIX1	Homo sapiens	Q8TDN6	Anti Tag CoIP	28514442
Intra	EBNA1BP2	Q99848	BRIX1	Homo sapiens	Q8TDN6	Y2H Array	32296183
Intra	EBNA1BP2	Q99848	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	32296183
Intra	EBNA1BP2	Q99848	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Intracranial Hypotension

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04129	EBNA1BP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	EBNA1BP2	VGNC	VGNC:40178
Rattus norvegicus	EBNA1BP2	RGD	RGD:1305762
Felis catus	EBNA1BP2	VGNC	VGNC:61705
Macaca mulatta	EBNA1BP2	VGNC	VGNC:71840
Mus musculus	EBNA1BP2	MGD	MGI:1916322
Bos taurus	EBNA1BP2	VGNC	VGNC:28299

Name
Email *

	Sorry, but the email address you supplied was invalid.