TRIM31 - tripartite motif containing 31 Gene

Homo sapiens

Also known as RNF; HCG1; HCGI; C6orf13

Gene ID: 11074 | Gene type: protein coding

About TRIM31

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:30,102,897-30,113,090 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 46 orthologues and 80 paralogues. Biased expression in colon (RPKM 26.2), urinary bladder (RPKM 20.1) and 5 other tissues.

Summary

This gene encodes a protein that functions as an E3 ubiquitin-protein Ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

TRIM31 Products(1)

mRNA	Protein	Name
NM_007028.5	NP_008959.3	E3 ubiquitin-protein ligase TRIM31

TRIM31 Protein Structure

zf-C3HC4_4

zf-B_box

0
100
200
300
400
425 a.a.

Protein Preferred Names

Protein Names

E3 ubiquitin-protein ligase TRIM31

RING-type E3 ubiquitin transferase TRIM31

Related Diseases

Diseases

Alias

Moyamoya Disease 1

Moyamoya Disease	Spontaneous Occlusion Of The Circle Of Willis
Mymy	Progressive Intracranial Arterial Occlusion
Moyamoya Syndrome	MYMY1
Cerebrovascular Moyamoya Disease	Moya-Moya Disease
Progressive Intracranial Occlusive Arteropathy	Idiopathic Moyamoya Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15036	TRIM31 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TRIM31	VGNC	VGNC:36327
Rattus norvegicus	TRIM31	RGD	RGD:1308607
Mus musculus	TRIM31	MGD	MGI:2385051

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