CLASRP - CLK4 associating serine/arginine rich protein Gene

Homo sapiens

Also known as CLASP; SWAP2; SFRS16

Gene ID: 11129 | Gene type: protein coding

About CLASRP

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:45,039,045-45,070,956 (from NCBI)

This gene has 16 transcripts (splice variants), 189 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 17.9), spleen (RPKM 17.1) and 25 other tissues.

Summary

Predicted to be involved in RNA splicing and mRNA processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CLASRP Products(2)

mRNA	Protein	Name
NM_001278439.2	NP_001265368.1	CLK4-associating serine/arginine rich protein isoform 2
NM_007056.3	NP_008987.2	CLK4-associating serine/arginine rich protein isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	27173435	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLASRP Protein Structure

DRY_EERY

0
200
400
600
674 a.a.

Protein Preferred Names

Protein Names

CLK4-associating serine/arginine rich protein

Clk4 associating SR-related protein

CLASRP Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CLASRP	Q8N2M8	CFAP20	Homo sapiens	Q9Y6A4	Validated Y2H	32296183
Intra	CLASRP	Q8N2M8	CLK3	Homo sapiens	P49761	Y2H Prey Pooling	32296183
Intra	CLASRP	Q8N2M8	CLK3	Homo sapiens	P49761	Validated Y2H	32296183
Intra	CLASRP	Q8N2M8	CLK3	Homo sapiens	P49761	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Color Agnosia

Developmental Coordination Disorder

Motor Skills Disorders

Astereognosia

Somatosensory Agnosia

Tactile Agnosia

Hypercholesterolemia, Familial, 4

Hypercholesterolemia, Autosomal Recessive	Arh
FHCL4	Autosomal Recessive Hypercholesterolemia
Arh1	Arh2
Autosomal Recessive Hypercholesterolemia 1	Autosomal Recessive Hypercholesterolemia 2
Fhcb1	Fhcb2
Hypercholesterolemia, Autosomal Recessive, 1, Formerly	Arh1, Formerly
Fhcb1, Formerly	Hypercholesterolemia, Autosomal Recessive, 2, Formerly
Arh2, Formerly	Fhcb2, Formerly
Familial Autosomal Recessive Hypercholesterolemia	Hypercholesterolemia, Familial, Autosomal Recessive
Hypercholesterolemia, Familial, Type 4

Mitral Valve Insufficiency

Mitral Regurgitation	Congenital Insufficiency Of Mitral Valve
Congenital Mitral Insufficiency	Congenital Mitral Regurgitation
Mitral Valve Incompetence	Mitral Valve Regurgitation
Mr - [Mitral Regurgitation]	Mi - [Mitral Incompetence]
Mitral Valve Annular Incompetency	Congenital Mitral Valve Incompetence
Congenital Mitral Valve Insufficiency	Congenital Mitral Valve Regurgitation
Congenital Mitral Incompetence

Mitral Valve Disease

Chronic Rheumatic Mitral Valve	Rheumatic Mitral Insufficiency
Disease Of Mitral Valve	Mitral Rh Valve Dis.
Rheumatic Disease Of Mitral Valve	Rheumatic Mitral Valve Changes
Rheumatic Mitral Valve Incompetence	Rheumatic Mitral Valve Regurgitation
Abnormality Of The Mitral Valve	Diseases Of Mitral Valve
Rheumatic Mitral Regurgitation

Tricuspid Valve Insufficiency

Tricuspid Regurgitation	Tricuspid Valve Regurgitation
Tricuspid Incompetence	Tr - [Tricuspid Regurgitation]
Tricuspid Valve Incompetency	Tricuspid Valve Annular Incompetency

Tricuspid Valve Disease

Rheumatic Tricuspid Valve Disease	Disease Of Tricuspid Valve
Rh. Tricuspid Valve Disease	Rheumatic Disease Of Tricuspid Valve
Tricuspid Disease	Tricuspid Valve Disorder

Specific Language Impairment

Language Impairment, Specific

Familial Hypercholesterolemia

Hyperlipoproteinemia Type Iia	Familial Hyperbetalipoproteinaemia
Familial Hypercholesteremia	Fredrickson Type Iia Hyperlipoproteinemia
Fredrickson Type Iia Lipidaemia	Hyperbetalipoproteinemia
Type Ii Hyperlipidemia	Familial Hypercholesterolæmia
Familial Hypercholesterolaemia	Fh
Hypercholesterolemia Familial	Hyperlipoproteinemia Type Ii
Hypercholesterolemia, Familial

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02746	CLASRP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CLASRP	MGD	MGI:1855695
Bos taurus	CLASRP	VGNC	VGNC:27391
Rattus norvegicus	CLASRP	RGD	RGD:1563538
Macaca mulatta	CLASRP	VGNC	VGNC:71198

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