FICD - FIC domain protein adenylyltransferase Gene

Homo sapiens

Also known as HYPE; HIP13; UNQ3041

Gene ID: 11153 | Gene type: protein coding

About FICD

This gene has 5 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in thyroid (RPKM 7.5), testis (RPKM 4.5) and 25 other tissues.

Summary

Enables several functions, including ATP binding activity; HSP70 protein binding activity; and chaperone binding activity. Involved in protein adenylylation; regulation of IRE1-mediated unfolded protein response; and response to endoplasmic reticulum stress. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

FICD Products(1)

mRNA	Protein	Name
NM_007076.3	NP_009007.2	protein adenylyltransferase FICD

FICD Protein Structure

Fic

0
100
200
300
400
458 a.a.

Protein Preferred Names

Protein Names

protein adenylyltransferase FICD

AMPylator FICD

Related Diseases

Diseases

Alias

Cone-Rod Dystrophy 13

CORD13

Dystrophy, Cone-Rod, Type 13

Alcoholic Psychosis

Psychoses, Alcoholic

Alcoholic Psychoses

Progressive Familial Heart Block

Hereditary Bundle Branch Defect	Hereditary Bundle Branch System Defect
Familial Lenegre Disease	Familial Lev Disease
Familial Lev-Lenegre Disease	Familial Pccd
Familial Progressive Heart Block	Pfhb
Bundle Branch Block	Hbbd
Lenegre Lev Disease	Lev Syndrome
Lev'S Disease	Lev-Lenègre Disease
Pccd	Progressive Cardiac Conduction Defect
Bundle-Branch Block

Schizotypal Personality Disorder

Schizotypal Personality

Cholestasis, Progressive Familial Intrahepatic, 1

PFIC1	Byler Disease
Cholestasis, Progressive Familial Intrahepatic 1	Progressive Familial Intrahepatic Cholestasis 1
Progressive Familial Intrahepatic Cholestasis Type 1	Fic1 Deficiency
Byler'S Disease	Cholestasis, Fatal Intrahepatic
Progressive Familial Intrahepatic Cholestasis	Severe Atp8b1 Deficiency
Fatal Intrahepatic Cholestasis	Cholestasis, Intrahepatic, Familial, Progressive, Type 1
Progressive Intrahepatic Cholestasis	Cholestasis, Progressive Familial Intrahepatic 3

Adult Hepatocellular Carcinoma

Adult Primary Hepatocellular Carcinoma	Adult Hepatoma
Adult Hcc

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04943	FICD Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	FICD	VGNC	VGNC:107705
Rattus norvegicus	FICD	RGD	RGD:1359391
Bos taurus	FICD	VGNC	VGNC:29007
Mus musculus	FICD	MGD	MGI:1098550
Macaca mulatta	FICD	VGNC	VGNC:82081
Canis familiaris	FICD	VGNC	VGNC:52933

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