WDFY2 - WD repeat and FYVE domain containing 2 Gene

Homo sapiens

Also known as PROF; WDF2; ZFYVE22

Gene ID: 115825 | Gene type: protein coding

About WDFY2

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:51,584,462-51,767,709 (from NCBI)

This gene has 3 transcripts (splice variants), 220 orthologues and 10 paralogues. Ubiquitous expression in skin (RPKM 5.8), bone marrow (RPKM 4.0) and 25 other tissues.

Summary

This gene encodes a protein that contains two WD domains and an FYVE zinc finger region. The function of this gene is unknown. An alternatively spliced transcript variant of this gene may exist. [provided by RefSeq, Jul 2008]

WDFY2 Products(1)

mRNA	Protein	Name
NM_052950.4	NP_443182.1	WD repeat and FYVE domain-containing protein 2

WDFY2 Protein Structure

WD40

FYVE

WD40

0
100
200
300
400 a.a.

Protein Preferred Names

Protein Names

WD repeat and FYVE domain-containing protein 2

WD40 and FYVE domain containing 2

WDFY2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	WDFY2	Q96P53	RPRM	Homo sapiens	Q9NS64	Y2H Array	32296183
Intra	WDFY2	Q96P53	RPRM	Homo sapiens	Q9NS64	Y2H Prey Pooling	32296183
Intra	WDFY2	Q96P53	RPRM	Homo sapiens	Q9NS64	Validated Y2H	32296183
Intra	WDFY2	Q96P53	YIF1A	Homo sapiens	O95070	Y2H Array	32296183
Intra	WDFY2	Q96P53	YIF1A	Homo sapiens	O95070	Y2H Prey Pooling	32296183
Intra	WDFY2	Q96P53	NUDC	Homo sapiens	Q9Y266	Anti Tag CoIP	33961781
Intra	WDFY2	Q96P53	NUDC	Homo sapiens	Q9Y266	Lumier	25036637
Intra	WDFY2	Q96P53	ARL6IP1	Homo sapiens	Q15041	Y2H Array	32296183
Intra	WDFY2	Q96P53	ARL6IP1	Homo sapiens	Q15041	Y2H Prey Pooling	32296183
Intra	WDFY2	Q96P53	SYP	Homo sapiens	P08247	Y2H Prey Pooling	32296183
Intra	WDFY2	Q96P53	SYP	Homo sapiens	P08247	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Hyperglobulinemic Purpura

Purpura, Hyperglobulinemic

Laryngeal Tuberculosis

Tuberculosis, Laryngeal

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15755	WDFY2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	WDFY2	RGD	RGD:1307337
Felis catus	WDFY2	VGNC	VGNC:67010
Canis familiaris	WDFY2	VGNC	VGNC:54388
Mus musculus	WDFY2	MGD	MGI:2442811
Bos taurus	WDFY2	VGNC	VGNC:53847
Macaca mulatta	WDFY2	VGNC	VGNC:97842

Name
Email *

	Sorry, but the email address you supplied was invalid.