2. Gene
  3. RPRM - reprimo, TP53 dependent G2 arrest mediator homolog Gene

RPRM - reprimo, TP53 dependent G2 arrest mediator homolog Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as REPRIMO

Gene ID: 56475 | Gene type: protein coding

About RPRM

Cytogenetic location: 2q23.3 Genomic coordinates (GRCh38): 2:153,477,338-153,478,762 (from NCBI)

This gene has 1 transcript (splice variant), 206 orthologues and 1 paralogue.

Summary

Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RPRM Products(1)

mRNA Protein Name
NM_019845.3 NP_062819.1 protein reprimo
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein reprimo

candidate mediator of the p53 dependent G2 arrest

RPRM Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra RPRM Q9NS64 SYT16 Homo sapiens Q17RD7
Y2H Array
32296183
Intra RPRM Q9NS64 SNX11 Homo sapiens Q9Y5W9
Validated Y2H
32296183
Intra RPRM Q9NS64 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra RPRM Q9NS64 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 GNG13 Homo sapiens Q9P2W3
Validated Y2H
32296183
Intra RPRM Q9NS64 BSCL2 Homo sapiens J3KQ12
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 BSCL2 Homo sapiens J3KQ12
Y2H Array
32296183
Intra RPRM Q9NS64 TMEM80 Homo sapiens Q96HE8
Y2H Array
32296183
Intra RPRM Q9NS64 TMEM80 Homo sapiens Q96HE8
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CLEC2D Homo sapiens Q9UHP7-3
Validated Y2H
32296183
Intra RPRM Q9NS64 CLEC2D Homo sapiens Q9UHP7-3
Y2H Array
32296183
Intra RPRM Q9NS64 CLEC2D Homo sapiens Q9UHP7-3
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CLEC17A Homo sapiens Q6ZS10
Y2H Array
32296183
Intra RPRM Q9NS64 CLEC17A Homo sapiens Q6ZS10
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 KCNJ6 Homo sapiens P48051
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 KCNJ6 Homo sapiens P48051
Y2H Array
32296183
Intra RPRM Q9NS64 STOM Homo sapiens P27105
Y2H Array
32296183
Intra RPRM Q9NS64 STOM Homo sapiens P27105
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra RPRM Q9NS64 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 TSPO2 Homo sapiens Q5TGU0
Y2H Array
32296183
Intra RPRM Q9NS64 TSPO2 Homo sapiens Q5TGU0
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra RPRM Q9NS64 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 ASGR2 Homo sapiens P07307-3
Y2H Array
32296183
Intra RPRM Q9NS64 MS4A4A Homo sapiens Q96JQ5
Y2H Array
32296183
Intra RPRM Q9NS64 MS4A4A Homo sapiens Q96JQ5
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CXorf66 Homo sapiens Q5JRM2
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CXorf66 Homo sapiens Q5JRM2
Y2H Array
32296183
Intra RPRM Q9NS64 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra RPRM Q9NS64 TM4SF18 Homo sapiens Q96CE8
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 TM4SF18 Homo sapiens Q96CE8
Y2H Array
32296183
Intra RPRM Q9NS64 SPACA1 Homo sapiens Q9HBV2
Y2H Array
32296183
Intra RPRM Q9NS64 SPACA1 Homo sapiens Q9HBV2
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 SLC18A1 Homo sapiens P54219-3
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 SLC18A1 Homo sapiens P54219-3
Y2H Array
32296183
Intra RPRM Q9NS64 BTNL9 Homo sapiens Q6UXG8-3
Y2H Array
32296183
Intra RPRM Q9NS64 BTNL9 Homo sapiens Q6UXG8-3
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 ADGRG3 Homo sapiens Q86Y34
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 ADGRG3 Homo sapiens Q86Y34
Y2H Array
32296183
Intra RPRM Q9NS64 C16orf54 Homo sapiens Q6UWD8
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 C16orf54 Homo sapiens Q6UWD8
Y2H Array
32296183
Intra RPRM Q9NS64 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra RPRM Q9NS64 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra RPRM Q9NS64 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 SUSD3 Homo sapiens Q96L08
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 SUSD3 Homo sapiens Q96L08
Y2H Array
32296183
Intra RPRM Q9NS64 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra RPRM Q9NS64 CLDN9 Homo sapiens O95484
Y2H Array
32296183
Intra RPRM Q9NS64 CLDN9 Homo sapiens O95484
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CLDN5 Homo sapiens O00501
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CLDN5 Homo sapiens O00501
Y2H Array
32296183
Intra RPRM Q9NS64 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
Intra RPRM Q9NS64 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 AMIGO1 Homo sapiens Q86WK6
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 AMIGO1 Homo sapiens Q86WK6
Y2H Array
32296183
Intra RPRM Q9NS64 SNX12 Homo sapiens Q9UMY4-1
Validated Y2H
32296183
Intra RPRM Q9NS64 TMEM86B Homo sapiens Q8N661
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 TMEM86B Homo sapiens Q8N661
Y2H Array
32296183
Intra RPRM Q9NS64 OPRD1 Homo sapiens P41143
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 OPRD1 Homo sapiens P41143
Y2H Array
32296183
Intra RPRM Q9NS64 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra RPRM Q9NS64 TMEM106C Homo sapiens Q9BVX2
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 TMEM106C Homo sapiens Q9BVX2
Y2H Array
32296183
Intra RPRM Q9NS64 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra RPRM Q9NS64 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CD69 Homo sapiens Q07108
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CD69 Homo sapiens Q07108
Y2H Array
32296183
Intra RPRM Q9NS64 LAPTM5 Homo sapiens Q13571
Y2H Array
32296183
Intra RPRM Q9NS64 LAPTM5 Homo sapiens Q13571
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 HHLA2 Homo sapiens Q9UM44
Y2H Array
32296183
Intra RPRM Q9NS64 HHLA2 Homo sapiens Q9UM44
Validated Y2H
32296183
Intra RPRM Q9NS64 HHLA2 Homo sapiens Q9UM44
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 FCGR1A Homo sapiens P12314
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 FCGR1A Homo sapiens P12314
Y2H Array
32296183
Intra RPRM Q9NS64 LPAR6 Homo sapiens P43657
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 LPAR6 Homo sapiens P43657
Y2H Array
32296183
Intra RPRM Q9NS64 GPR37L1 Homo sapiens O60883
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 GPR37L1 Homo sapiens O60883
Y2H Array
32296183
Intra RPRM Q9NS64 CD33 Homo sapiens P20138
Y2H Array
32296183
Intra RPRM Q9NS64 CD33 Homo sapiens P20138
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 GJB3 Homo sapiens O75712
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 GJB3 Homo sapiens O75712
Y2H Array
32296183
Intra RPRM Q9NS64 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 GJB5 Homo sapiens O95377
Y2H Array
32296183
Intra RPRM Q9NS64 FKBP7 Homo sapiens Q9Y680
Y2H Array
32296183
Intra RPRM Q9NS64 FKBP7 Homo sapiens Q9Y680
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 FKBP7 Homo sapiens Q9Y680
Validated Y2H
32296183
Intra RPRM Q9NS64 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
Intra RPRM Q9NS64 EMP1 Homo sapiens P54849
Y2H Array
32296183
Intra RPRM Q9NS64 EMP1 Homo sapiens P54849
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CD53 Homo sapiens P19397
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CD53 Homo sapiens P19397
Y2H Array
32296183
Intra RPRM Q9NS64 PDZK1IP1 Homo sapiens Q13113
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 PDZK1IP1 Homo sapiens Q13113
Y2H Array
32296183
Intra RPRM Q9NS64 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 CLDN7 Homo sapiens O95471
Y2H Array
32296183
Intra RPRM Q9NS64 SMIM3 Homo sapiens Q9BZL3
Y2H Array
32296183
Intra RPRM Q9NS64 SMIM3 Homo sapiens Q9BZL3
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
Intra RPRM Q9NS64 BNIP3 Homo sapiens Q12983
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 BNIP3 Homo sapiens Q12983
Y2H Array
32296183
Intra RPRM Q9NS64 GJA5 Homo sapiens P36382
Y2H Array
32296183
Intra RPRM Q9NS64 GJA5 Homo sapiens P36382
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 TMEM79 Homo sapiens Q9BSE2
Y2H Prey Pooling
32296183
Intra RPRM Q9NS64 TMEM79 Homo sapiens Q9BSE2
Y2H Array
32296183
Intra RPRM Q9NS64 SLC38A1 Homo sapiens Q9H2H9
Y2H Array
32296183
Intra RPRM Q9NS64 SLC38A1 Homo sapiens Q9H2H9
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12219 RPRM Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus RPRM VGNC VGNC:80346
Mus musculus RPRM MGD MGI:1915124
Bos taurus RPRM VGNC VGNC:34129
Rattus norvegicus RPRM RGD RGD:1595512
Macaca mulatta RPRM VGNC VGNC:77093