2. Gene
  3. Aicda - activation-induced cytidine deaminase Gene

Aicda - activation-induced cytidine deaminase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Aid; Arp2

Gene ID: 11628 | Gene type: protein coding

About Aicda

Summary

Enables cytidine deaminase activity. Involved in cytidine deamination and isotype switching. Acts upstream of or within cellular response to lipopolysaccharide and defense response to bacterium. Predicted to be part of protein-containing complex. Predicted to be active in P-body and nucleus. Is expressed in several structures, including immune system; lower urogenital tract; lung; reproductive system; and urethra epithelium. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Orthologous to human AICDA (activation induced cytidine deaminase). [provided by Alliance of Genome Resources, Apr 2022]

Aicda Products(1)

mRNA Protein Name
NM_009645.2 NP_033775.1 single-stranded DNA cytosine deaminase
Protein Preferred Names Protein Names

single-stranded DNA cytosine deaminase

activation induced deaminase

cytidine aminohydrolase

Aicda Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Aicda Q9WVE0 Top2b Mus musculus Q64511
Anti Bait CoIP
21186367
Intra
Aicda Q9WVE0 Top2b Mus musculus Q64511
Anti Tag CoIP
21186367
Intra
Aicda Q9WVE0 Top2b Mus musculus Q64511
Pull Down
21186367
Cross
Aicda Q9WVE0 GADD45A Homo sapiens P24522
Anti Tag CoIP
23820005
Intra
Aicda Q9WVE0 Ptbp2 Mus musculus Q91Z31
Anti Bait CoIP
21186367
Intra
Aicda Q9WVE0 Ptbp2 Mus musculus Q91Z31
Pull Down
21186367
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Aicda Proteins

Cat. No. Product Name Accession Purity
HY-P72074 AICDA Protein, Mouse (His-Myc) Q9WVE0 (M1-F198) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10337 OXM-7 Agonist / Unkown
HY-RS00488 AICDA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aicda NCBI NCBI:57379