2. Gene
  3. HSPA12B - heat shock protein family A (Hsp70) member 12B Gene

HSPA12B - heat shock protein family A (Hsp70) member 12B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as C20orf60

Gene ID: 116835 | Gene type: protein coding

About HSPA12B

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:3,732,685-3,753,111 (from NCBI)

This gene has 2 transcripts (splice variants), 193 orthologues and 4 paralogues. Broad expression in fat (RPKM 15.5), spleen (RPKM 11.6) and 19 other tissues.

Summary

The protein encoded by this gene contains an atypical heat shock protein 70 (HSP70) ATPase domain and is therefore a distant member of the mammalian HSP70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

HSPA12B Products(3)

mRNA Protein Name
NM_001197327.2 NP_001184256.1 heat shock 70 kDa protein 12B isoform 2
NM_001318322.2 NP_001305251.1 heat shock 70 kDa protein 12B isoform 3
NM_052970.5 NP_443202.3 heat shock 70 kDa protein 12B isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock 70 kDa protein 12B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06421 HSPA12B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta HSPA12B VGNC VGNC:84531
Felis catus HSPA12B VGNC VGNC:80114
Mus musculus HSPA12B MGD MGI:1919880
Canis familiaris HSPA12B VGNC VGNC:53543
Rattus norvegicus HSPA12B RGD RGD:1312004