CLRN3 - clarin 3 Gene

Homo sapiens

Also known as TMEM12; USH3AL1

Gene ID: 119467 | Gene type: protein coding

About CLRN3

This gene has 1 transcript (splice variant), 198 orthologues and 2 paralogues. Biased expression in small intestine (RPKM 43.6), colon (RPKM 38.2) and 5 other tissues.

Summary

Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

CLRN3 Products(1)

mRNA	Protein	Name
NM_152311.5	NP_689524.1	clarin-3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLRN3 Protein Structure

Claudin_2

0
100
200
226 a.a.

Protein Preferred Names

Protein Names

clarin-3

transmembrane protein 12

CLRN3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CLRN3	Q8NCR9	NME2P1	Homo sapiens	O60361	Anti Tag CoIP	28514442
Intra	CLRN3	Q8NCR9	NME2P1	Homo sapiens	O60361	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Usher Syndrome, Type Iiia

Usher Syndrome Type 3	Ush3
Usher Syndrome Type 3a	USH3A
Usher Syndrome, Type Iii	Usher Syndrome, Type 3
Usher Syndrome, Type 3a	Usher Syndrome Type Iiia
Usher Syndrome 3a	Usher'S Syndrome Type 3
Usher Syndrome Iii	Usher Syndrome Type Iii

Usher Syndrome

Deafness-Retinitis Pigmentosa Syndrome	Dystrophia Retinae Pigmentosa-Dysostosis Syndrome
Graefe-Usher Syndrome	Hallgren Syndrome
Usher'S Syndrome	Retinitis Pigmentosa-Deafness Syndrome
Retinitis Pigmentosa-Hearing Loss Syndrome	Ush
Usher Syndromes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02838	CLRN3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CLRN3	VGNC	VGNC:27464
Canis familiaris	CLRN3	VGNC	VGNC:39361
Rattus norvegicus	CLRN3	RGD	RGD:1305043
Mus musculus	CLRN3	MGD	MGI:2142022
Macaca mulatta	CLRN3	VGNC	VGNC:106025

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