2. Gene
  3. Cd19 - CD19 antigen Gene

Cd19 - CD19 antigen Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 12478 | Gene type: protein coding

About Cd19

Summary

Involved in several processes, including B-1 B cell differentiation; positive regulation of phosphatidylinositol 3-kinase activity; and positive regulation of release of sequestered calcium ion into cytosol. Acts upstream of or within B cell receptor signaling pathway. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD19 (CD19 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd19 Products(2)

mRNA Protein Name
NM_001357091.2 NP_001344020.1 B-lymphocyte antigen CD19 isoform 2 precursor
NM_009844.3 NP_033974.2 B-lymphocyte antigen CD19 isoform 1 precursor
Protein Preferred Names Protein Names

B-lymphocyte antigen CD19

differentiation antigen CD19

Recombinant Cd19 Proteins

Cat. No. Product Name Accession Purity
HY-P74328 CD19 Protein, Mouse (HEK293, His) P25918 (G17-G287) ≥95%
HY-P77527 CD19 Protein, Mouse (Biotinylated, HEK293, His) P25918 (G17-G287) ≥95%

Related Agents

Approval
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9963 Blinatumomab Inhibitor 98.78% Unkown
HY-P99113 Inebilizumab Inhibitor 99.00% Unkown
HY-P99338 Tisagenlecleucel / Unkown
Clinical Phase
Inhibitory Antibodies (5)
Cat. No. Product Name Effect
Purity Phase
HY-P99711 Loncastuximab Inhibitor 95.00% Phase 3
HY-P99761 Obexelimab Inhibitor 95.00% Phase 3
HY-P99285 Denintuzumab Inhibitor 95.00% Phase 2
HY-P99868 Duvortuxizumab / Phase 1
HY-P990017 Englumafusp alfa Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153084 CD19 CAR mRNA (Mouse) / Unkown
HY-153084A CD19 CAR mRNA (Human) / Unkown
HY-153233 CD19 car mRNA (Mouse)-LNP ≥90.0% Unkown
HY-153234 CD19 car circRNA-LNP / Unkown
HY-153085 CD19 CAR circRNA / Unkown
Inhibitory Antibodies (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99113A Inebilizumab (FUT8-KO) 97% Unkown
HY-P99976 Anti-Mouse CD19 Antibody (1D3) Inhibitor 95.00% Unkown
HY-P99914 Emfizatamab / Unkown
HY-P99577 Taplitumomab / Unkown
HY-P990571 Coltuximab Inhibitor / Unkown
HY-P990729 Budoprutug / Unkown
HY-P990694 Zeripatamig / Unkown
HY-P990349 Anti-CD19 Antibody Inhibitor / Unkown
HY-P990870 Anti-CD19 Antibody (4G7) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd19 NCBI NCBI:930
Macaca fascicularis Cd19 NCBI NCBI:102145514
Macaca mulatta Cd19 NCBI NCBI:705211