Cdx1 - caudal type homeobox 1 Gene

Mus musculus

Also known as Cdx; Cdx-1

Gene ID: 12590 | Gene type: protein coding

About Cdx1

Summary

Enables DNA-binding transcription factor activity. Involved in regulation of somitogenesis. Acts upstream of or within anterior/posterior pattern specification; bone morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; embryo ectoderm; embryo mesenchyme; genitourinary system; and intestine. Orthologous to human CDX1 (caudal type homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Cdx1 Products(1)

mRNA	Protein	Name
NM_009880.3	NP_034010.3	homeobox protein CDX-1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	22015720	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	17158164	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within anterior/posterior pattern specification	IGI IGI: Inferred from genetic interaction	11784046	MGI
acts upstream of or within anterior/posterior pattern specification	IMP IMP: Inferred from mutant phenotype	7585967	MGI
acts upstream of or within bone morphogenesis	IGI IGI: Inferred from genetic interaction	11784046	MGI
acts upstream of or within bone morphogenesis	IMP IMP: Inferred from mutant phenotype	11784046	MGI
acts upstream of or within pattern specification process	IMP IMP: Inferred from mutant phenotype	11959827	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	7585967	MGI
involved in regulation of somitogenesis	IMP IMP: Inferred from mutant phenotype	22015720	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

homeobox protein CDX-1

caudal type homeo box 1	caudal type homeobox transcription factor 1
caudal-type homeobox protein 1

Cdx1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Cdx1	P18111	TBP	Homo sapiens	P20226	Anti Tag CoIP	17158164

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02429	CDX1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cdx1	NCBI	NCBI:1044

Name
Email *

	Sorry, but the email address you supplied was invalid.