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  2. Ctse - cathepsin E Gene

Ctse - cathepsin E Gene

Mus musculus

Also known as CE; CatE; A430072O03Rik; C920004C08Rik

Gene ID: 13034 | Gene type: protein coding

About Ctse

Chromosome 1: 131,566,044-131,603,243 forward strand.GRCm39:CM000994.3

This gene has 3 transcripts (splice variants), 142 orthologues, 8 paralogues and is associated with 17 phenotypes. Biased expression in stomach adult (RPKM 438.1), bladder adult (RPKM 7.7) and 3 other tissues.

Summary

This gene encodes a member of the peptidase A1 family of aspartate proteases and preproprotein that is proteolytically processed to generate a mature protein product. The encoded protein may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. Homozygous knockout mice for this gene exhibit lysosomal storage disorder, impaired Autophagy, mitochondrial abnormalities, dermatitis, and reduced weight gain in an obesity model. [provided by RefSeq, Aug 2015]

Ctse Products(2)

mRNA Protein Name
NM_007799.3 NP_031825.2 cathepsin E preproprotein
NM_007799.3 NP_031825.2 cathepsin E preproprotein

Ctse Protein Structure

A1_Propeptide

A1_Propeptide: pfam07966 (21 - 49)

pepsin_retropepsin_like

pepsin_retropepsin_like: cl11403 (78 - 393)

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  • 100
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  • 300
  • 397 a.a.
Protein Preferred Names Protein Names

cathepsin E

Recombinant Ctse Proteins

Cat. No. Product Name Accession Purity
HY-P7751 Cathepsin E Protein, Mouse (HEK293, His) P70269 (S60-P397) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctse NCBI NCBI:1510
Rattus norvegicus Ctse NCBI NCBI:25424