CD200R1 - CD200 receptor 1 Gene

Homo sapiens

Also known as OX2R; MOX2R; CD200R; HCRTR2

Gene ID: 131450 | Gene type: protein coding

About CD200R1

Cytogenetic location: 3q13.2 Genomic coordinates (GRCh38): 3:112,921,205-112,975,103 (from NCBI)

This gene has 5 transcripts (splice variants), 235 orthologues and 1 paralogue. Broad expression in spleen (RPKM 4.6), placenta (RPKM 2.9) and 22 other tissues.

Summary

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

CD200R1 Products(4)

mRNA	Protein	Name
NM_138806.4	NP_620161.1	cell surface glycoprotein CD200 receptor 1 isoform a precursor
NM_138939.3	NP_620385.1	cell surface glycoprotein CD200 receptor 1 isoform b precursor
NM_138940.3	NP_620386.1	cell surface glycoprotein CD200 receptor 1 isoform c precursor
NM_170780.3	NP_740750.1	cell surface glycoprotein CD200 receptor 1 isoform d precursor

CD200R1 Protein Structure

C2-set_2

0
100
200
300
325 a.a.

Protein Preferred Names

Protein Names

cell surface glycoprotein CD200 receptor 1

CD200 cell surface glycoprotein receptor

Recombinant CD200R1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72749	CD200R1 Protein, Human (HEK293, His)	Q8TD46-4 (A27-L266)	≥95%
HY-P75622	CD200R1 Protein, Human (HEK293, His-Fc)	Q8TD46-4 (A27-L266)	≥95%
HY-P77599	CD200R1 Protein, Human (HEK293, Fc)	Q8TD46-4 (A27-L266)	≥95%
HY-P77600	CD200R1 Protein, Human (HEK293, His-Avi)	Q8TD46-4 (A27-L266)	≥95%
HY-P77601	CD200R1 Protein, Human (Biotinylated, HEK293, His-Avi)	Q8TD46-4 (A27-L266)	≥95%

Related Diseases

Diseases

Alias

Human Herpesvirus 8

HHV8S	Human Herpesvirus 8, Susceptibility To
Hhv-8	Hhv-8, Susceptibility To
HHV8	Kaposi Sarcoma

Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1

Nasu-Hakola Disease	Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy
Plosl	Nhd
Presenile Dementia With Bone Cysts	Plo-Sl
PLOSL1	Dementia, Prefrontal, With Bone Cysts
Dementia, Progressive, With Lipomembranous Polycystic Osteodysplasia	Brain-Bone-Fat Disease
Progressive Dementia With Lipomembranous Polycystic Osteodysplasia	Brain-Bone-Fat Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02206	CD200R1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS02207	CD200R1L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CD200R1	RGD	RGD:61837
Macaca mulatta	CD200R1	VGNC	VGNC:70845
Macaca fascicularis	CD200R1	NCBI	NCBI:102139962
Mus musculus	CD200R1	NCBI	NCBI:57781
Others	CD200R1	NCBI

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