2. Gene
  3. SYNPR - synaptoporin Gene

SYNPR - synaptoporin Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SPO

Gene ID: 132204 | Gene type: protein coding

About SYNPR

This gene has 15 transcripts (splice variants), 129 orthologues and 3 paralogues. Restricted expression toward brain (RPKM 14.4).

Summary

Predicted to be located in neuron projection and synaptic vesicle. Predicted to be integral component of membrane. Predicted to be active in synaptic vesicle membrane. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

SYNPR Products(2)

mRNA Protein Name
NM_001130003.2 NP_001123475.1 synaptoporin isoform 1
NM_144642.5 NP_653243.1 synaptoporin isoform 2 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SYNPR Protein Structure

MARVEL

MARVEL: Membrane-associating domain (6 - 196)

  • 0
  • 100
  • 200
  • 265 a.a.
Protein Preferred Names Protein Names

synaptoporin

SYNPR Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
SYNPR Q8TBG9 LNPK Homo sapiens Q9C0E8
Anti Tag CoIP
33961781
Intra
SYNPR Q8TBG9 C4orf3 Homo sapiens Q8WVX3-2
Validated Y2H
32296183
Intra
SYNPR Q8TBG9 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
25416956
Intra
SYNPR Q8TBG9 FATE1 Homo sapiens Q969F0
Y2H Array
25416956
Intra
SYNPR Q8TBG9 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Intra
SYNPR Q8TBG9 DOLK Homo sapiens Q9UPQ8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Nutritional Optic Neuropathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14100 SYNPR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SYNPR RGD RGD:708366
Macaca mulatta SYNPR VGNC VGNC:78138
Canis familiaris SYNPR VGNC VGNC:47037
Felis catus SYNPR VGNC VGNC:80730
Mus musculus SYNPR MGD MGI:1919253
Bos taurus SYNPR VGNC VGNC:35532