PAGE3 - PAGE family member 3 Gene

Homo sapiens

Also known as CT16.6; GAGED1; PAGE-3

Gene ID: 139793 | Gene type: protein coding

About PAGE3

Cytogenetic location: Xp11.21 Genomic coordinates (GRCh38): X:55,258,415-55,264,916 (from NCBI)

This gene has 2 transcripts (splice variants), 22 orthologues and 22 paralogues. Restricted expression toward testis (RPKM 1.3).

Summary

This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2015]

PAGE3 Products(3)

mRNA	Protein	Name
NM_001017931.3	NP_001017931.3	P antigen family member 3
NM_001171252.2	NP_001164723.2	P antigen family member 3
NM_001303613.2	NP_001290542.2	P antigen family member 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PAGE3 Protein Structure

GAGE

0
100
113 a.a.

Protein Preferred Names

Protein Names

P antigen family member 3

G antigen family D member 1

PAGE3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PAGE3	Q5JUK9	FAM9B	Homo sapiens	Q8IZU0	Validated Y2H	25416956
Intra	PAGE3	Q5JUK9	MEOX1	Homo sapiens	P50221	Y2H Prey Pooling	25416956
Intra	PAGE3	Q5JUK9	MEOX1	Homo sapiens	P50221	Validated Y2H	25416956
Intra	PAGE3	Q5JUK9	SGTA	Homo sapiens	O43765	Y2H Array	32296183
Intra	PAGE3	Q5JUK9	SGTA	Homo sapiens	O43765	Y2H Prey Pooling	32296183
Intra	PAGE3	Q5JUK9	SGTB	Homo sapiens	Q96EQ0	Y2H Prey Pooling	32296183
Intra	PAGE3	Q5JUK9	SGTB	Homo sapiens	Q96EQ0	Validated Y2H	32296183
Intra	PAGE3	Q5JUK9	SGTB	Homo sapiens	Q96EQ0	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09975	PAGE3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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