1. Gene
  2. F8 - coagulation factor VIII Gene

F8 - coagulation factor VIII Gene

Mus musculus

Also known as Cf8; Cf-8; FVIII

Gene ID: 14069 | Gene type: protein coding

About F8

Summary

Predicted to enable copper ion binding activity and oxidoreductase activity. Predicted to be involved in blood coagulation, intrinsic pathway. Predicted to act upstream of or within acute-phase response and hemostasis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and liver and biliary system. Used to study Factor VIII deficiency. Human ortholog(s) of this gene implicated in Factor VIII deficiency. Orthologous to human F8 (coagulation Factor VIII). [provided by Alliance of Genome Resources, Apr 2022]

F8 Products(3)

mRNA Protein Name
NM_001161373.1 NP_001154845.1 coagulation factor VIII isoform 2 precursor
NM_001161374.1 NP_001154846.1 coagulation factor VIII isoform 3 precursor
NM_007977.2 NP_032003.2 coagulation factor VIII isoform 1 precursor
Protein Preferred Names Protein Names

coagulation factor VIII

Factor VIII

procoagulant component

Orthologs Information

Species Symbol Source ID
Homo sapiens F8 NCBI NCBI:2157
Felis catus F8 NCBI NCBI:101092751
Macaca fascicularis F8 NCBI NCBI:102125498
Rattus norvegicus F8 NCBI NCBI:302470