Fzd9 - frizzled class receptor 9 Gene

Mus musculus

Also known as Fz9; mfz9

Gene ID: 14371 | Gene type: protein coding

About Fzd9

Summary

Enables Wnt-activated receptor activity. Involved in several processes, including bone regeneration; negative regulation of skeletal muscle acetylcholine-gated channel clustering; and positive regulation of bone mineralization. Acts upstream of or within B cell differentiation; learning or memory; and neuroblast proliferation. Located in filopodium membrane and perinuclear region of cytoplasm. Is expressed in several structures, including central nervous system; embryo mesenchyme; gonad; sensory organ; and skeleton. Used to study Williams-Beuren syndrome. Orthologous to human FZD9 (Frizzled class receptor 9). [provided by Alliance of Genome Resources, Apr 2022]

Fzd9 Products(1)

mRNA	Protein	Name
NM_010246.1	NP_034376.1	frizzled-9 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables Wnt receptor activity	IDA IDA: Inferred from direct assay	24860427	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within B cell differentiation	IMP IMP: Inferred from mutant phenotype	15572594	MGI
involved in bone regeneration	IMP IMP: Inferred from mutant phenotype	24391920	MGI
acts upstream of or within learning or memory	IMP IMP: Inferred from mutant phenotype	15930120	MGI
involved in negative regulation of skeletal muscle acetylcholine-gated channel clustering	IMP IMP: Inferred from mutant phenotype	24860427	MGI
acts upstream of or within neuroblast proliferation	IMP IMP: Inferred from mutant phenotype	15930120	MGI
involved in ossification	IMP IMP: Inferred from mutant phenotype	21402791	MGI
involved in positive regulation of bone mineralization	IMP IMP: Inferred from mutant phenotype	21402791	MGI
involved in positive regulation of canonical Wnt signaling pathway	IMP IMP: Inferred from mutant phenotype	24860427	MGI
involved in regulation of skeletal muscle acetylcholine-gated channel clustering	IDA IDA: Inferred from direct assay	24860427	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in filopodium membrane	IDA IDA: Inferred from direct assay	10198163	MGI
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	10198163	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	10198163	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

frizzled-9

frizzled homolog 9	fz-9
mFz3

Recombinant Fzd9 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79115	Frizzled-9 Protein, Mouse (HEK293, mFc)	Q9R216 (L24-D186)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05185	FZD9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fzd9	NCBI	NCBI:8326

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