2. Gene
  3. AMDHD1 - amidohydrolase domain containing 1 Gene

AMDHD1 - amidohydrolase domain containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HMFT1272

Gene ID: 144193 | Gene type: protein coding

About AMDHD1

This gene has 4 transcripts (splice variants) and 201 orthologues. Biased expression in liver (RPKM 25.7), adrenal (RPKM 6.0) and 1 other tissue.

Summary

Predicted to enable imidazolonepropionase activity. Predicted to be involved in histidine catabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

AMDHD1 Products(1)

mRNA Protein Name
NM_152435.3 NP_689648.2 probable imidazolonepropionase
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AMDHD1 Protein Structure

(73 - 392)

  • 0
  • 100
  • 200
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  • 400
  • 426 a.a.
Protein Preferred Names Protein Names

probable imidazolonepropionase

amidohydrolase domain-containing protein 1

AMDHD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
AMDHD1 Q96NU7 KLHL23 Homo sapiens Q8NBE8
Anti Tag CoIP
33961781
Intra
AMDHD1 Q96NU7 KLHL23 Homo sapiens Q8NBE8
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Hemochromatosis, Type 2b

Hemochromatosis Type 2b

HFE2B

Hemochromatosis 2b
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00645 AMDHD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus AMDHD1 MGD MGI:1919011
Bos taurus AMDHD1 VGNC VGNC:25860
Macaca mulatta AMDHD1 VGNC VGNC:69729
Rattus norvegicus AMDHD1 RGD RGD:1308879
Felis catus AMDHD1 VGNC VGNC:59764