2. Gene
  3. CTRL - chymotrypsin like Gene

CTRL - chymotrypsin like Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CTRL1

Gene ID: 1506 | Gene type: protein coding

About CTRL

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,929,574-67,931,862 (from NCBI)

This gene has 8 transcripts (splice variants), 202 orthologues and 1 paralogue. Restricted expression toward pancreas (RPKM 884.9).

Summary

This gene encodes a serine-type endopeptidase with chymotrypsin- and elastase-2-like activities. The gene encoding this zymogen is expressed specifically in the pancreas and likely functions as a digestive Enzyme. [provided by RefSeq, Sep 2016]

CTRL Products(1)

mRNA Protein Name
NM_001907.3 NP_001898.1 chymotrypsin-like protease CTRL-1 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables serine-type peptidase activity IDA
IDA: Inferred from direct assay
9065485 GOA
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
9065485 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CTRL Protein Structure

Trypsin

Trypsin: Trypsin (34 - 257)

  • 0
  • 100
  • 200
  • 264 a.a.
Protein Preferred Names Protein Names

chymotrypsin-like protease CTRL-1

Recombinant CTRL Proteins

Cat. No. Product Name Accession Purity
HY-P70033 CTRL-1 Protein, Human (HEK293, His) P40313 (C19-N264) ≥95%

Related Diseases

Diseases Alias
Netherton Syndrome

NETH

Ns

Netherton Disease

Comel-Netherton Syndrome

Erythroderma, Ichthyosiform, With Hypotrichosis And Hyper-Ige

Bamboo Hair Syndrome

Ichthyosis Linearis Circumflexa

Ichthyosiform Erythroderma With Hypotrichosis And Hyper-Ige

Ilc

Nts

N Syndrome
Necrotizing Ulcerative Gingivitis

Acute Necrotizing Ulcerative Gingivitis

Anug

Vincent Angina

Vincent'S Disease

Acute Necrotising Ulcerative Gingivitis

Acute Necrotising Ulcerative Gingivostomatitis

Acute Necrotizing Ulcerative Gingivostomatitis

Acute Ulceromembranous Gingivitis

Angina - Vincents

Early Acute Necrotising Gingivitis

Trench Mouth

Vincent'S Angina

Vincent'S Angina - Pharyngitis

Vincent'S Infection, Any Site

Acute Membranous Gingivitis

Fusospirillary Gingivitis

Fusospirillosis

Phagedenic Gingivitis

Vincent'S Gingivitis

Vincent'S Infection

Vincent'S Stomatitis

Gingivitis, Necrotizing Ulcerative
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Cataract

Cataracts

Cat - [Cataract]

Cataract Form

Lens Opacity

Lens Opacities
Mantle Cell Lymphoma

Lymphoma, Mantle Cell

Lcm

Mcl

Mantle Zone Lymphoma

Lymphoma Mantle-Cell

Lymphoma, Mantle-Cell

Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

Diffuse Small Cleaved-Cell Lymphoma

Diffuse Small Cleaved Cell Malignant Lymphoma

Small Cleaved Cell Non-Hodgkin Lymphoma

Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

Malignant Lymphomatous Polyposis

Malignant Small Cell, Noncleaved, Diffuse Lymphoma

Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

Cleaved Cell Lymphoma

Small Cell Mantle Cell Lymphoma

Small Cleaved Cell Malignant Lymphoma
Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers
Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150087 Ctrl-CF4-S2 / Unkown
HY-RS03320 CTRL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CTRL VGNC VGNC:39707
Macaca mulatta CTRL VGNC VGNC:71551
Mus musculus CTRL MGD MGI:88558
Felis catus CTRL VGNC VGNC:61264
Rattus norvegicus CTRL RGD RGD:621501
Others CTRL NCBI