2. Gene
  3. Mst1 - macrophage stimulating 1 (hepatocyte growth factor-like) Gene

Mst1 - macrophage stimulating 1 (hepatocyte growth factor-like) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hgfl; D3F15S2h; DNF15S2h; D9H3F15S2

Gene ID: 15235 | Gene type: protein coding

About Mst1

Summary

Predicted to enable receptor tyrosine kinase binding activity. Acts upstream of or within several processes, including embryo implantation; mammary duct terminal end bud growth; and positive regulation of mammary gland epithelial cell proliferation. Located in vacuole. Is expressed in esophagus epithelium; liver; liver parenchyma; pharynx epithelium; and stomach proventricular region epithelium. Orthologous to several human genes including MST1 (macrophage stimulating 1). [provided by Alliance of Genome Resources, Apr 2022]

Mst1 Products(2)

mRNA Protein Name
NM_008243.3 NP_032269.3 hepatocyte growth factor-like protein precursor
NM_008243.3 NP_032269.3 hepatocyte growth factor-like protein precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within embryo implantation IDA
IDA: Inferred from direct assay
12606483 MGI
acts upstream of or within mammary duct terminal end bud growth IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within mammary gland development IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within negative regulation of epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within positive regulation of mammary gland epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within regulation of macrophage chemotaxis IMP
IMP: Inferred from mutant phenotype
25049204 MGI
acts upstream of or within regulation of receptor signaling pathway via JAK-STAT IMP
IMP: Inferred from mutant phenotype
25049204 MGI
Cellular Component GO Annotation Evidence Reference Source
located in vacuole IDA
IDA: Inferred from direct assay
25049204 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatocyte growth factor-like protein

MSP

macrophage stimulatory protein

Recombinant Mst1 Proteins

Cat. No. Product Name Accession Purity
HY-P701103 MSP/MST1 Protein, Mouse (C677A, HEK293) P26928/NP_032269 (Q19-E716, C677A) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-15514 Merestinib Inhibitor 99.99% Phase 2
HY-15514A Merestinib dihydrochloride Inhibitor 99.36% Phase 2
Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100526 XMU-MP-1 Inhibitor 99.24% Unkown
HY-128206 I3MT-3 Inhibitor 99.98% Unkown
HY-151257 IHMT-MST1-58 Inhibitor 99.05% Unkown
HY-164595 IHMT-MST1-39 / Unkown
HY-P1790 Axltide / Unkown
HY-RS08729 MST1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08730 MST1R Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mst1 NCBI NCBI:4485