1. Gene
  2. Jchain - immunoglobulin joining chain Gene

Jchain - immunoglobulin joining chain Gene

Mus musculus

Also known as Igj; Jch; 9530090F24Rik

Gene ID: 16069 | Gene type: protein coding

About Jchain

Summary

Enables IgA binding activity and protein-macromolecule adaptor activity. Contributes to immunoglobulin receptor binding activity. Predicted to be involved in several processes, including defense response to Other organism; glomerular filtration; and positive regulation of respiratory burst. Part of dimeric IgA immunoglobulin complex. Is expressed in intestine; serum; and spleen. Orthologous to human JCHAIN (joining chain of multimeric IgA and IgM). [provided by Alliance of Genome Resources, Apr 2022]

Jchain Products(1)

mRNA Protein Name
NM_152839.4 NP_690052.2 immunoglobulin J chain precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables IgA binding IDA
IDA: Inferred from direct assay
17237408 MGI
contributes to immunoglobulin receptor binding IMP
IMP: Inferred from mutant phenotype
17237408 MGI
enables protein-macromolecule adaptor activity IDA
IDA: Inferred from direct assay
17237408 MGI
Cellular Component GO Annotation Evidence Reference Source
part of dimeric IgA immunoglobulin complex IMP
IMP: Inferred from mutant phenotype
17237408 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immunoglobulin J chain

immunoglobulin joining gene (not J region)

Recombinant Jchain Proteins

Cat. No. Product Name Accession Purity
HY-P71744 Immunoglobulin J chain Protein, Mouse (P.pastoris, His) P01592 (G22-D159) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Jchain NCBI NCBI:3512