2. Gene
  3. Il1rn - interleukin 1 receptor antagonist Gene

Il1rn - interleukin 1 receptor antagonist Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as IL-1ra; F630041P17Rik

Gene ID: 16181 | Gene type: protein coding

About Il1rn

Summary

Predicted to enable cytokine receptor binding activity. Acts upstream of or within Insulin secretion and lipid metabolic process. Located in extracellular region and vesicle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human IL1RN (interleukin 1 receptor antagonist). [provided by Alliance of Genome Resources, Apr 2022]

Il1rn Products(3)

mRNA Protein Name
NM_001039701.3 NP_001034790.1 interleukin-1 receptor antagonist protein isoform 2 precursor
NM_001159562.1 NP_001153034.1 interleukin-1 receptor antagonist protein isoform 3
NM_031167.5 NP_112444.1 interleukin-1 receptor antagonist protein isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within insulin secretion IMP
IMP: Inferred from mutant phenotype
12975454 MGI
acts upstream of or within lipid metabolic process IMP
IMP: Inferred from mutant phenotype
12975454 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
15240711 MGI
located in vesicle IDA
IDA: Inferred from direct assay
15240711 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-1 receptor antagonist protein

IL-1RN

IL1 inhibitor

IRAP

Recombinant Il1rn Proteins

Cat. No. Product Name Accession Purity
HY-P72566 IL-1RA/IL-1RN Protein, Mouse P25085-1 (R27-Q178) ≥95%
HY-P700197AF Animal-Free IL-1RA/IL-1RN Protein, Mouse (His) P25085-1 (R27-Q178) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06727 IL1RN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il1rn NCBI NCBI:3557
Macaca fascicularis Il1rn NCBI NCBI:102126145
Rattus norvegicus Il1rn NCBI NCBI:60582