2. Gene
  3. Il5ra - interleukin 5 receptor, alpha Gene

Il5ra - interleukin 5 receptor, alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Il5r; CD125; CDw125

Gene ID: 16192 | Gene type: protein coding

About Il5ra

Summary

Predicted to enable cytokine binding activity and cytokine receptor activity. Acts upstream of or within cellular response to organic substance; inflammatory response to antigenic stimulus; and regulation of interleukin-5 production. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in early conceptus. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL5RA (interleukin 5 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il5ra Products(1)

mRNA Protein Name
NM_008370.2 NP_032396.1 interleukin-5 receptor subunit alpha precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
10848907 MGI
acts upstream of or within regulation of interleukin-5 production IMP
IMP: Inferred from mutant phenotype
10848907 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-5 receptor subunit alpha

IL-5 receptor alpha chain

IL-5 receptor subunit alpha

IL-5R subunit alpha

Recombinant Il5ra Proteins

Cat. No. Product Name Accession Purity
HY-P72540 IL-5R alpha Protein, Mouse (HEK293, His) P21183 (D18-H339) ≥95%
HY-P75864 IL-5R alpha Protein, Mouse (sf9, His) P21183 (M1-V328) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06773 IL5RA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9923A Benralizumab (anti-IL5RA ) 99.60% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il5ra NCBI NCBI:3568