WBP2NL - WBP2 N-terminal like Gene

Homo sapiens

Also known as PAWP; GRAMD7

Gene ID: 164684 | Gene type: protein coding

About WBP2NL

Cytogenetic location: 22q13.2 Genomic coordinates (GRCh38): 22:41,998,788-42,058,371 (from NCBI)

This gene has 10 transcripts (splice variants), 87 orthologues and 1 paralogue. Biased expression in testis (RPKM 7.0) and thyroid (RPKM 0.3).

Summary

WBP2NL is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during oocyte fertilization (Wu et al., 2007 [PubMed 17289678]).[supplied by OMIM, Mar 2008]

WBP2NL Products(1)

mRNA	Protein	Name
NM_152613.3	NP_689826.2	postacrosomal sheath WW domain-binding protein

WBP2NL Protein Structure

GRAM

0
100
200
309 a.a.

Protein Preferred Names

Protein Names

postacrosomal sheath WW domain-binding protein

WW domain-binding protein 2-like

Related Diseases

Diseases

Alias

Spermatogenic Failure 9

Male Infertility Due To Globozoospermia	SPGF9
Male Infertility Due To Round-Headed Spermatozoa	Globozoospermia, Complete
Globozoospermia, Total	Globozoospermia
Globozoospermia Syndrome	Round-Headed Sperm Syndrome
Globozoospermia Complete	Globozoospermia Total

Constrictive Pericarditis

Pericarditis, Constrictive	Pericarditis Constrictive
Pericarditis Calculosa	Hutinel-Pick Syndrome
Chronic Tamponade	Chronic Pericardial Constriction
Pick Syndrome Of Heart	Pick Disease Of Heart
Concretio Cordis	Calcareous Pericarditis

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15751	WBP2NL Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	WBP2NL	VGNC	VGNC:67008
Rattus norvegicus	WBP2NL	RGD	RGD:1586458
Macaca mulatta	WBP2NL	VGNC	VGNC:79707
Canis familiaris	WBP2NL	VGNC	VGNC:48342
Bos taurus	WBP2NL	VGNC	VGNC:36873
Mus musculus	WBP2NL	MGD	MGI:1921966

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