PRSS35 - serine protease 35 Gene

Homo sapiens

Also known as C6orf158; dJ223E3.1

Gene ID: 167681 | Gene type: protein coding

About PRSS35

This gene has 1 transcript (splice variant), 266 orthologues and 1 paralogue. Broad expression in ovary (RPKM 5.2), brain (RPKM 3.9) and 14 other tissues.

Summary

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PRSS35 Products(2)

mRNA	Protein	Name
NM_001170423.2	NP_001163894.1	inactive serine protease 35 precursor
NM_153362.3	NP_699193.2	inactive serine protease 35 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	27499296	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRSS35 Protein Structure

Trypsin

0
100
200
300
413 a.a.

Protein Preferred Names

Protein Names

inactive serine protease 35

protease, serine 35

PRSS35 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PRSS35	Q8N3Z0	C1QBP	Homo sapiens	Q07021	Anti Tag CoIP	27499296

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Pontocerebellar Hypoplasia, Type 6

Pontocerebellar Hypoplasia Type 6	PCH6
Fatal Infantile Encephalopathy With Mitochondrial Respiratory Chain Defects	Encephalopathy, Fatal Infantile, With Mitochondrial Respiratory Chain Defects
Encephalopathy Fatal Infantile With Mitochondrial Respiratory Chain Defects	Pontocerebellar Hypoplasia 6
Hypoplasia, Pontocerebellar, Type 6

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11255	PRSS35 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRSS35	RGD	RGD:1311282
Macaca mulatta	PRSS35	VGNC	VGNC:76299
Canis familiaris	PRSS35	VGNC	VGNC:45066
Felis catus	PRSS35	VGNC	VGNC:64398
Bos taurus	PRSS35	VGNC	VGNC:33418
Mus musculus	PRSS35	MGD	MGI:2444800

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