GIMAP7 - GTPase, IMAP family member 7 Gene

Homo sapiens

Also known as IAN7; hIAN7

Gene ID: 168537 | Gene type: protein coding

About GIMAP7

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,514,872-150,521,073 (from NCBI)

This gene has 1 transcript (splice variant), 201 orthologues and 7 paralogues. Broad expression in lymph node (RPKM 74.8), spleen (RPKM 59.3) and 19 other tissues.

Summary

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

GIMAP7 Products(1)

mRNA	Protein	Name
NM_153236.4	NP_694968.1	GTPase IMAP family member 7

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTP binding	IDA IDA: Inferred from direct assay	23454188	GOA
enables GTPase activity	IDA IDA: Inferred from direct assay	23454188	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	23454188	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	23454188	GOA
enables protein homodimerization activity	IPI IPI: Inferred from physical interaction	23454188	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in GTP metabolic process	IDA IDA: Inferred from direct assay	23454188	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in lipid droplet	IDA IDA: Inferred from direct assay	23454188	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GIMAP7 Protein Structure

AIG1

0
100
200
300 a.a.

Protein Preferred Names

Protein Names

GTPase IMAP family member 7

IAN-7

GIMAP7 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GIMAP7	Q8NHV1	GIMAP2	Homo sapiens	Q9UG22	GTPase Assay	23454188
Intra	GIMAP7	Q8NHV1	GIMAP7	Homo sapiens	Q8NHV1	Solution Sedimentation	23454188
Intra	GIMAP7	Q8NHV1	GIMAP7	Homo sapiens	Q8NHV1	X-Ray Diffraction	23454188

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05427	GIMAP7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GIMAP7	RGD	RGD:1565750
Macaca mulatta	GIMAP7	VGNC	VGNC:81316
Canis familiaris	GIMAP7	VGNC	VGNC:41218
Mus musculus	GIMAP7	MGD	MGI:1349657

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