GIMAP2 - GTPase, IMAP family member 2 Gene

Homo sapiens

Also known as IAN12; IMAP2; HIMAP2

Gene ID: 26157 | Gene type: protein coding

About GIMAP2

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,685,706-150,693,641 (from NCBI)

This gene has 3 transcripts (splice variants), 59 orthologues and 7 paralogues. Broad expression in lymph node (RPKM 31.9), spleen (RPKM 29.6) and 22 other tissues.

Summary

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

GIMAP2 Products(1)

mRNA	Protein	Name
NM_015660.3	NP_056475.1	GTPase IMAP family member 2

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	21059949	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	23454188	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in lipid droplet	IDA IDA: Inferred from direct assay	23454188	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GIMAP2 Protein Structure

AIG1

0
100
200
300
337 a.a.

Protein Preferred Names

Protein Names

GTPase IMAP family member 2

immune-associated nucleotide-binding protein 12

Related Diseases

Diseases

Alias

Noonan Syndrome 8

NS8	Noonan Syndrome, Type 8

Behcet Syndrome

Behcet Disease	Behcet'S Syndrome
Behcet'S Disease	Behçet Disease
Bd	Adamantiades-Behcet Disease
Triple Symptom Complex	Behçet'S Disease
Behet'S Syndrome	Bd Syndrome
Behçet Syndrome	Behçet'S Syndrome
Behcet Triple Symptom Complex	Malignant Aphthosis
Old Silk Route Disease	Adamantiades-Behçet Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05423	GIMAP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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