2. Gene
  3. Epcam - epithelial cell adhesion molecule Gene

Epcam - epithelial cell adhesion molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EGP; Ly74; gp40; CD326; EGP-2; TROP1; Egp314; Ep-CAM; EpCAM1; Tacsd1; GA733-2; Tacstd1

Gene ID: 17075 | Gene type: protein coding

About Epcam

Summary

Predicted to enable cadherin binding activity involved in cell-cell adhesion. Acts upstream of or within ureteric bud development. Located in cell surface. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study congenital diarrhea 5 with tufting enteropathy. Human ortholog(s) of this gene implicated in congenital diarrhea 5 with tufting enteropathy and hereditary nonpolyposis colorectal Cancer type 8. Orthologous to human EPCAM (epithelial cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]

Epcam Products(1)

mRNA Protein Name
NM_008532.2 NP_032558.2 epithelial cell adhesion molecule precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in ureteric bud development IEP
IEP: Inferred from expression pattern
16545622 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
17599412 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

epithelial cell adhesion molecule

Trop-1 protein

epithelial glycoprotein 314

lymphocyte antigen 74

mEGP314

panepithelial glycoprotein 314

protein 289A

tumor-associated calcium signal transducer 1

Recombinant Epcam Proteins

Cat. No. Product Name Accession Purity
HY-P70900 EpCAM/TROP1 Protein, Mouse (HEK293, Fc) Q99JW5 (Q24-T266) ≥95%
HY-P78704 EpCAM/TROP1 Protein, Mouse (HEK293, His) Q99JW5/AAH05618.1 (Q24-T266) ≥95%

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111183 Neocarzinostatin ≥99.0% Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9954 Catumaxomab 98.56% Unkown
Clinical Phase
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P99328 Tucotuzumab ≥95.0% Phase 2
HY-P99592 Solitomab Inhibitor 98.22% Phase 1
HY-P99282 Citatuzumab bogatox Inducer / Phase 1
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15897 LDN-212854 Inhibitor 99.70% Unkown
HY-168885 ZSH-512 / Unkown
HY-RS04420 EPCAM Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991034 Trevotamig Inhibitor / Unkown
HY-P990862 Anti-CD326/EpCAM Antibody (Ber-EP4) / Unkown
HY-P990642 Oportuzumab Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epcam NCBI NCBI:4072
Rattus norvegicus Epcam NCBI NCBI:171577
Macaca mulatta Epcam NCBI NCBI:677680