2. Gene
  3. Nodal - nodal Gene

Nodal - nodal Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tg.413d

Gene ID: 18119 | Gene type: protein coding

About Nodal

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. Homozygous knockout mice for this gene exhibit early embryonic lethality, while expression of a hypomorphic allele results in defects in anteroposterior and left-right patterning. [provided by RefSeq, Aug 2016]

Nodal Products(1)

mRNA Protein Name
NM_013611.5 NP_038639.2 nodal preproprotein
Protein Preferred Names Protein Names

nodal

Recombinant Nodal Proteins

Cat. No. Product Name Accession Purity
HY-P79080 Nodal Protein, Mouse P43021 (H245-L354) ≥95%

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0016 Dronedarone 99.93% Unkown
HY-17611 Etripamil Antagonist 98.80% Unkown
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10432 A 83-01 Inhibitor 99.41% Unkown
HY-RS09409 NODAL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-123196 CVT-2759 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nodal NCBI NCBI:4838