2. Gene
  3. ARID3A - AT-rich interaction domain 3A Gene

ARID3A - AT-rich interaction domain 3A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as DRIL1; DRIL3; BRIGHT; E2FBP1

Gene ID: 1820 | Gene type: protein coding

About ARID3A

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:925,732-975,939 (from NCBI)

This gene has 7 transcripts (splice variants), 191 orthologues and 2 paralogues. Broad expression in placenta (RPKM 13.1), bone marrow (RPKM 2.3) and 16 other tissues.

Summary

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

ARID3A Products(1)

mRNA Protein Name
NM_005224.3 NP_005215.1 AT-rich interactive domain-containing protein 3A
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19214191 GOA
Cellular Component GO Annotation Evidence Reference Source
located in membrane raft IDA
IDA: Inferred from direct assay
21955986 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARID3A Protein Structure

ARID

ARID: ARID/BRIGHT DNA binding domain (238 - 326)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 593 a.a.
Protein Preferred Names Protein Names

AT-rich interactive domain-containing protein 3A

ARID domain-containing 3A

ARID3A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ARID3A Q99856 MORF4L1 Homo sapiens Q9UBU8-2
Validated Y2H
32296183
Intra
ARID3A Q99856 REP15 Homo sapiens Q6BDI9
Y2H Array
32296183
Intra
ARID3A Q99856 REP15 Homo sapiens Q6BDI9
Y2H Prey Pooling
32296183
Intra
ARID3A Q99856 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Intra
ARID3A Q99856 BTK Homo sapiens Q06187
Anti Bait CoIP
19214191
Intra
ARID3A Q99856 BTK Homo sapiens Q06187
Density Sedimentation
19214191
Intra
ARID3A Q99856 NOTCH2NLA Homo sapiens Q7Z3S9
Y2H Array
25416956
Intra
ARID3A Q99856 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
ARID3A Q99856 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00969 ARID3A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ARID3A VGNC VGNC:69930
Bos taurus ARID3A VGNC VGNC:26126
Canis familiaris ARID3A VGNC VGNC:38095
Mus musculus ARID3A MGD MGI:1328360
Rattus norvegicus ARID3A RGD RGD:1305299
Felis catus ARID3A VGNC VGNC:59914