2. Gene
  3. EEF1B2 - eukaryotic translation elongation factor 1 beta 2 Gene

EEF1B2 - eukaryotic translation elongation factor 1 beta 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as EF1B; EEF1B; EEF1B1

Gene ID: 1933 | Gene type: protein coding

About EEF1B2

Cytogenetic location: 2q33.3 Genomic coordinates (GRCh38): 2:206,159,609-206,162,928 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 182 orthologues, 2 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 282.5), lymph node (RPKM 249.8) and 25 other tissues.

Summary

This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008]

EEF1B2 Products(3)

mRNA Protein Name
NM_001037663.2 NP_001032752.1 elongation factor 1-beta
NM_001959.4 NP_001950.1 elongation factor 1-beta
NM_021121.4 NP_066944.1 elongation factor 1-beta
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16169070 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
8743958 GOA
colocalizes with endoplasmic reticulum IDA
IDA: Inferred from direct assay
8743958 GOA
NOT located in nucleus IDA
IDA: Inferred from direct assay
12426392 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EEF1B2 Protein Structure

EF-1_beta_acid

EF-1_beta_acid: Eukaryotic elongation factor 1 beta central acidic region (103 - 130)

EF1_GNE

EF1_GNE: EF-1 guanine nucleotide exchange domain (139 - 225)

  • 0
  • 100
  • 200
  • 225 a.a.
Protein Preferred Names Protein Names

elongation factor 1-beta

EF-1-beta

Recombinant EEF1B2 Proteins

Cat. No. Product Name Accession Purity
HY-P76898 EEF1B2 Protein, Human (His) P24534 (G2-I225) ≥95%

Related Diseases

Diseases Alias
Cystic Echinococcosis

Echinococcus Granulosus Infection

Echinococcus Granulosus Infection Of Lung

Echinococcus Granulosus

Echinococcus Granulosus Infection Of Thyroid

Echinococcus Granulosus Infectious Disease

Echinococcus Granulosus Infectious Disease Of Liver

Echinococcus Granulosus Infectious Disease Of Thyroid

Liver Echinococcus Granulosus

Lung Echinococcus Granulosus

Thyroid Echinococcus Granulosus

Unilocular Echinococcosis

Unilocular Hydatid Disease

Hydatid Disease

Hydatidosis

Echinococcosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04176 EEF1B2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EEF1B2 MGD MGI:1929520
Macaca mulatta EEF1B2 VGNC VGNC:104523
Rattus norvegicus EEF1B2 RGD RGD:1311415
Bos taurus EEF1B2 VGNC VGNC:54422
Felis catus EEF1B2 VGNC VGNC:82529
Canis familiaris EEF1B2 VGNC VGNC:57381
Others EEF1B2 NCBI