EEF2KMT - eukaryotic elongation factor 2 lysine methyltransferase Gene

Homo sapiens (human)

Also known as EFM3; SB153; FAM86A; eEF2-KMT

Gene ID: 196483 | Gene type: protein coding

About EEF2KMT

Summary

Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine trimethylation. Located in cytoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

EEF2KMT Products(1)

mRNA	Protein	Name
XM_005255157.5	XP_005255214.1	protein-lysine N-methyltransferase EEF2KMT isoform X1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA
enables protein-lysine N-methyltransferase activity	IDA IDA: Inferred from direct assay	25231979	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in peptidyl-lysine trimethylation	IDA IDA: Inferred from direct assay	25231979	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	23349634	GOA
part of protein-containing complex	IDA IDA: Inferred from direct assay	23349634	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein-lysine N-methyltransferase EEF2KMT

eEF2-lysine methyltransferase	family with sequence similarity 86, member A
protein FAM86A	putative protein N-methyltransferase FAM86A

EEF2KMT Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	EEF2KMT	Q96G04	ZNF35	Homo sapiens	P13682	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	ZNF35	Homo sapiens	P13682	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	ZNF213	Homo sapiens	O14771	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	ZNF213	Homo sapiens	O14771	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	PRKAR1B	Homo sapiens	P31321	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	PRKAR1B	Homo sapiens	P31321	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	KIAA1328	Homo sapiens	Q86T90	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	KIAA1328	Homo sapiens	Q86T90	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	IFT88	Homo sapiens	Q13099	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	IFT88	Homo sapiens	Q13099	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	TRIP13	Homo sapiens	Q15645	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	TRIP13	Homo sapiens	Q15645	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	ZNF620	Homo sapiens	Q6ZNG0	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	ZNF620	Homo sapiens	Q6ZNG0	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	PRTFDC1	Homo sapiens	Q9NRG1	Validated Y2H	32296183
Intra	EEF2KMT	Q96G04	PRTFDC1	Homo sapiens	Q9NRG1	Y2H Array	25416956
Intra	EEF2KMT	Q96G04	PRTFDC1	Homo sapiens	Q9NRG1	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	PRTFDC1	Homo sapiens	Q9NRG1	Y2H Prey Pooling	25416956
Intra	EEF2KMT	Q96G04	PRTFDC1	Homo sapiens	Q9NRG1	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	LNX1	Homo sapiens	Q8TBB1	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	LNX1	Homo sapiens	Q8TBB1	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	HPRT1	Homo sapiens	P00492	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	HPRT1	Homo sapiens	P00492	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183
Intra	EEF2KMT	Q96G04	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	EEF2KMT	Q96G04	NR0B1	Homo sapiens	P51843	Y2H Prey Pooling	32296183
Intra	EEF2KMT	Q96G04	NR0B1	Homo sapiens	P51843	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

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