CYP4Z1 - cytochrome P450 family 4 subfamily Z member 1 Gene

Homo sapiens

Also known as CYP4A20

Gene ID: 199974 | Gene type: protein coding

About CYP4Z1

Cytogenetic location: 1p33 Genomic coordinates (GRCh38): 1:47,055,525-47,118,318 (from NCBI)

This gene has 2 transcripts (splice variants), 328 orthologues and 12 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. This gene is part of a cluster of Cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008]

CYP4Z1 Products(1)

mRNA	Protein	Name
NM_178134.3	NP_835235.1	cytochrome P450 4Z1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables arachidonate 14,15-epoxygenase activity	IDA IDA: Inferred from direct assay	29018033	GOA
enables fatty acid in-chain hydroxylase activity	IDA IDA: Inferred from direct assay	19090726	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in arachidonate metabolic process	IDA IDA: Inferred from direct assay	29018033	GOA
involved in lauric acid metabolic process	IDA IDA: Inferred from direct assay	19090726	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in endoplasmic reticulum membrane	IDA IDA: Inferred from direct assay	15059886	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CYP4Z1 Protein Structure

p450

0
100
200
300
400
505 a.a.

Protein Preferred Names

Protein Names

cytochrome P450 4Z1

CYPIVZ1

Related Diseases

Diseases

Alias

Bietti Crystalline Corneoretinal Dystrophy

BCD	Bietti Crystalline Dystrophy
Bietti Tapetoretinal Degeneration With Marginal Corneal Dystrophy	Bietti Crystalline Retinopathy
Bietti'S Crystalline Dystrophy	Crystalline Retinopathy
Dystrophy, Corneoretinal, Crystalline, Bietti

Breast Adenoma

Ademoma - Breast

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-152159	CYP4Z1-IN-1	Inhibitor	/	Unkown
HY-RS03485	CYP4Z1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-139002	CYP4Z1-IN-2	Inhibitor	/	Unkown

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