2. Gene
  3. Cxcl5 - chemokine (C-X-C motif) ligand 5 Gene

Cxcl5 - chemokine (C-X-C motif) ligand 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as LIX; Cxcl6; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II

Gene ID: 20311 | Gene type: protein coding

About Cxcl5

Summary

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils and to have homeostatic and inflammatory functions. In mouse, deficiency of this gene is associated with increased lung inflammation that is neutrophil-dependent. [provided by RefSeq, May 2013]

Cxcl5 Products(1)

mRNA Protein Name
NM_009141.3 NP_033167.2 C-X-C motif chemokine 5 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within leukocyte homeostasis IMP
IMP: Inferred from mutant phenotype
20643340 MGI
acts upstream of or within regulation of chemokine production IMP
IMP: Inferred from mutant phenotype
20643340 MGI
acts upstream of or within regulation of neutrophil mediated killing of gram-negative bacterium IMP
IMP: Inferred from mutant phenotype
20643340 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
20643340 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-X-C motif chemokine 5

cytokine LIX

granulocyte chemotactic protein-2

small inducible cytokine B subfamily, member 5

small inducible cytokine subfamily B, member 15

small-inducible cytokine B5

Recombinant Cxcl5 Proteins

Cat. No. Product Name Accession Purity
HY-P7383 LIX/CXCL5 Protein, Mouse (74a.a, CHO) P50228 (V45-A118) ≥95%
HY-P72791 LIX/CXCL5 Protein, Mouse P50228 (A41-Q132) ≥95%
HY-P700173AF Animal-Free LIX/CXCL5 Protein, Mouse (His) P50228 (V45-A118) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120501 B022 Inhibitor 99.37% Unkown
HY-163475 CXCL-CXCR1/2-IN-1 Inhibitor 99.64% Unkown
HY-149393 RIPK3-IN-3 Inhibitor / Unkown
HY-RS03393 CXCL5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxcl5 NCBI NCBI:6374