1. Gene
  2. Cx3cl1 - chemokine (C-X3-C motif) ligand 1 Gene

Cx3cl1 - chemokine (C-X3-C motif) ligand 1 Gene

Mus musculus

Also known as FK; CX3C; Cxc3; Scyd1; ABCD-3; D8Bwg0439e

Gene ID: 20312 | Gene type: protein coding

About Cx3cl1

Summary

Enables CX3C Chemokine Receptor binding activity and chemokine activity. Acts upstream of or within several processes, including angiogenesis involved in wound healing; leukocyte chemotaxis; and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in several cellular components, including cell surface; neuron projection; and neuronal cell body. Is expressed in several structures, including brain; genitourinary system; gut; nose; and respiratory system. Human ortholog(s) of this gene implicated in Cor pulmonale and common cold. Orthologous to human CX3CL1 (C-X3-C motif chemokine ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Cx3cl1 Products(1)

mRNA Protein Name
NM_009142.3 NP_033168.2 fractalkine precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables CX3C chemokine receptor binding IDA
IDA: Inferred from direct assay
18971423 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell body IDA
IDA: Inferred from direct assay
12815711 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
12815711 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
12815711 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
28612258 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fractalkine

C-X3-C motif chemokine 1

CX3C membrane-anchored chemokine

neurotactin

small inducible cytokine subfamily D, 1

small-inducible cytokine D1

Recombinant Cx3cl1 Proteins

Cat. No. Product Name Accession Purity
HY-P72686 Fractalkine/CX3CL1 Protein, Mouse (HEK293, His) O35188 (Q25-R337) ≥95%
HY-P78113 Fractalkine/CX3CL1 Protein, Mouse (Biotinylated, HEK293, His-Avi) O35188 (Q25-T336) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Cx3cl1 NCBI NCBI:6376
Canis familiaris Cx3cl1 NCBI NCBI:487265
Macaca fascicularis Cx3cl1 NCBI NCBI:102117496
Rattus norvegicus Cx3cl1 NCBI NCBI:89808