2. Gene
  3. Ptk6 - PTK6 protein tyrosine kinase 6 Gene

Ptk6 - PTK6 protein tyrosine kinase 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BRK; Sik; tks; Tksk

Gene ID: 20459 | Gene type: protein coding

About Ptk6

Summary

Predicted to enable identical protein binding activity; non-membrane spanning protein tyrosine kinase activity; and signaling receptor binding activity. Involved in intestinal epithelial cell differentiation and negative regulation of growth. Located in nucleus. Is expressed in several structures, including gut; liver; and skin. Orthologous to human PTK6 (protein tyrosine kinase 6). [provided by Alliance of Genome Resources, Apr 2022]

Ptk6 Products(2)

mRNA Protein Name
NM_001356304.1 NP_001343233.1 protein-tyrosine kinase 6 isoform 2
NM_009184.2 NP_033210.1 protein-tyrosine kinase 6 isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in intestinal epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
16782882 MGI
involved in negative regulation of growth IMP
IMP: Inferred from mutant phenotype
16782882 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
12200423 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein-tyrosine kinase 6

src-related intestinal kinase

tyrosine kinase identified from skin

Recombinant Ptk6 Proteins

Cat. No. Product Name Accession Purity
HY-P72856 Brk Protein, Mouse (sf9, His-GST) Q64434 (M1-V451) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-110244 Tilfrinib Inhibitor 99.69% Unkown
HY-108333 SB-633825 Inhibitor 98.52% Unkown
HY-148065 FMF-06-098-1 98.77% Unkown
HY-115514A BRK inhibitor P21d hydrochloride Inhibitor ≥98.0% Unkown
HY-139660 PROTAC PTK6 ligand-1 95.03% Unkown
HY-RS11403 PTK6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-163214 (S)-PROTAC PTK6 ligand-1-(2S,4R)-O-CH2-O-hygric acid / Unkown
HY-163215 (S)-PROTAC PTK6 ligand-O-4,4-dimethylpiperidine-Boc / Unkown
HY-163216 PROTAC PTK6 ligand-O-4,4-dimethylpiperidine-Boc / Unkown
HY-163217 PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc / Unkown
HY-163218 PROTAC PTK6 ligand-1-(2S,4R)-O-CH2-O-hygric acid / Unkown
HY-163224 (S)-PROTAC PTK6 ligand-O-C2-O-piperidine-Boc / Unkown
HY-163228 PROTAC PTK6 ligand-O-C2-O-piperidine-Boc / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptk6 NCBI NCBI:5753