2. Gene
  3. Spn - sialophorin Gene

Spn - sialophorin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cd43; Ly48; Galgp; Ly-48; A630014B01Rik

Gene ID: 20737 | Gene type: protein coding

About Spn

Summary

Enables heat shock protein binding activity. Involved in leukocyte tethering or rolling and positive regulation of T cell migration. Acts upstream of or within several processes, including positive regulation of macromolecule metabolic process; regulation of T cell activation; and regulation of defense response. Located in basement membrane; external side of plasma membrane; and uropod. Is integral component of plasma membrane. Orthologous to human SPN (sialophorin). [provided by Alliance of Genome Resources, Apr 2022]

Spn Products(2)

mRNA Protein Name
NM_001037810.2 NP_001032899.1 leukosialin precursor
NM_009259.5 NP_033285.1 leukosialin precursor
Protein Preferred Names Protein Names

leukosialin

3E8 antigen

B-cell differentiation antigen LP-3

leukocyte sialoglycoprotein

lymphocyte antigen 48

Recombinant Spn Proteins

Cat. No. Product Name Accession Purity
HY-P75404 CD43 Protein, Mouse (HEK293, Fc) P15702 (D20-G248) ≥95%
HY-P78258 CD43 Protein, Mouse (HEK293, His) P15702 (D20-G248) ≥95%

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107434 Molindone Antagonist / Unkown
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149004 SLF1081851 Inhibitor 98.11% Unkown
HY-150254A SLB1122168 formic Inhibitor 99.91% Unkown
HY-162655 SLF80821178 99.70% Unkown
HY-150254 SLB1122168 Inhibitor / Unkown
HY-149004A SLF1081851 TFA Inhibitor / Unkown
HY-149004B SLF1081851 hydrochloride / Unkown
HY-156408 Spns2-IN-1 Inhibitor / Unkown
HY-162655A SLF80821178 hydrochloride Inhibitor / Unkown
HY-P10312 SPN009 Agonist / Unkown
HY-RS13689 SPN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13690 SPNS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13691 SPNS2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13692 SPNS3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-107434S Molindone-d8 Inhibitor 99.2% Unkown
HY-12450 Lomofungin Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spn NCBI NCBI:6693
Macaca fascicularis Spn NCBI NCBI:102147271
Rattus norvegicus Spn NCBI NCBI:24796