2. Gene
  3. Star - steroidogenic acute regulatory protein Gene

Star - steroidogenic acute regulatory protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as stARD1; D8Ertd419e

Gene ID: 20845 | Gene type: protein coding

About Star

Summary

Predicted to enable Cholesterol binding activity. Acts upstream of or within cellular lipid metabolic process; glucocorticoid metabolic process; and regulation of steroid biosynthetic process. Located in mitochondrion. Is expressed in several structures, including adrenal gland; extraembryonic component; and reproductive system. Used to study congenital adrenal hyperplasia. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia. Orthologous to human STAR (steroidogenic acute regulatory protein). [provided by Alliance of Genome Resources, Apr 2022]

Star Products(1)

mRNA Protein Name
NM_011485.5 NP_035615.2 steroidogenic acute regulatory protein, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cholesterol binding IDA
IDA: Inferred from direct assay
12011452 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular lipid metabolic process IMP
IMP: Inferred from mutant phenotype
9326645 MGI
acts upstream of or within glucocorticoid metabolic process IMP
IMP: Inferred from mutant phenotype
9326645 MGI
acts upstream of or within regulation of steroid biosynthetic process IDA
IDA: Inferred from direct assay
7961770 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
7961770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

steroidogenic acute regulatory protein, mitochondrial

START domain-containing protein 1

luteinizing hormone-induced protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15483 DY131 99.72% Unkown
HY-Y0740 4-Methoxybenzaldehyde 99.67% Unkown
HY-D1208 CDP-Star 94.40% Unkown
HY-143656 SH379 / Unkown
HY-161384 WJM-715 Inhibitor / Unkown
HY-N12102 Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside Inhibitor / Unkown
HY-N12136 1α-Hydroxy-3-deoxypseudoanisatin / Unkown
HY-P10780 RFRP-3 (mouse) / Unkown
HY-RS13875 STAR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-Y0740S 4-Methoxybenzaldehyde-d1 / Unkown
HY-Y0740S1 4-Methoxybenzaldehyde-d3 / Unkown
HY-N0368S2 Linalool-d6 / Unkown
HY-Y0740S2 4-Methoxybenzaldehyde-d2 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Star NCBI NCBI:6770
Canis familiaris Star NCBI NCBI:475588
Macaca fascicularis Star NCBI NCBI:102132972