2. Gene
  3. Aurkc - aurora kinase C Gene

Aurkc - aurora kinase C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as AIE1; AIK3; IAK3; ARK-3; Stk13

Gene ID: 20871 | Gene type: protein coding

About Aurkc

Chromosome 7: 6,998,299-7,006,090 forward strand.GRCm39:CM001000.3

This gene has 5 transcripts (splice variants), 99 orthologues, 2 paralogues and is associated with 5 phenotypes. Biased expression in testis adult (RPKM 2.8), ovary adult (RPKM .2) and 1 other tissue.

Summary

Enables protein kinase activity. Acts upstream of or within protein autophosphorylation. Located in chromosome, centromeric region and meiotic spindle midzone. Is expressed in gonad. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to human AURKC (Aurora Kinase C). [provided by Alliance of Genome Resources, Apr 2022]

Aurkc Products(3)

mRNA Protein Name
NM_020572.2 NP_065597.2 aurora kinase C isoform b
NM_001080966.1 NP_001074435.1 aurora kinase C isoform b
NM_001080965.1 NP_001074434.1 aurora kinase C isoform a

Aurkc Protein Structure

PKc_like

PKc_like: cl21453 (8 - 274)

  • 0
  • 100
  • 200
  • 276 a.a.
Protein Preferred Names Protein Names

aurora kinase C

aurora 3

aurora B

aurora-related kinase 3

aurora/IPL1-related kinase 3

aurora/Ipl1/Eg2 protein 1

serine/threonine kinase 13 (aurora/IPL-like)

serine/threonine-protein kinase 13

serine/threonine-protein kinase aurora-C

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120279A CFI-400437 Inhibitor / Unkown
HY-123610 BRD-7880 Inhibitor / Unkown
HY-160691 GW814408X / Unkown
HY-RS01273 AURKC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01274 Aurkc Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01275 AURKC Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-119948 AKCI Modulator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aurkc NCBI NCBI:6795