Ido2 - indoleamine 2,3-dioxygenase 2 Gene

Mus musculus

Also known as Ido-2; Indol1; C230043N17Rik

Gene ID: 209176 | Gene type: protein coding

About Ido2

Chromosome 8: 25,021,908-25,066,349 reverse strand.GRCm39:CM001001.3

This gene has 4 transcripts (splice variants), 91 orthologues and is associated with 7 phenotypes. Biased expression in liver adult (RPKM 13.5), genital fat pad adult (RPKM 2.6) and 1 other tissue.

Summary

Enables indoleamine 2,3-dioxygenase activity. Acts upstream of or within tryptophan catabolic process to kynurenine. Located in cytoplasm. Is expressed in corpus striatum. Orthologous to human IDO2 (indoleamine 2,3-dioxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ido2 Products(1)

mRNA	Protein	Name
NM_145949.2	NP_666061.3	indoleamine 2,3-dioxygenase 2

Ido2 Protein Structure

IDO

0
100
200
300
405 a.a.

Protein Preferred Names

Protein Names

indoleamine 2,3-dioxygenase 2

indoleamine 2,3-dioxygenase-like protein 1

indoleamine-pyrrole 2,3 dioxygenase-like 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-100687	GNF-PF-3777	Inhibitor	98.03%	Unkown
HY-151093	IDO2-IN-1	Inhibitor	98.86%	Unkown
HY-145280	IDO1/2-IN-1	Inhibitor	98.06%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ido2	NCBI	NCBI:169355

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