2. Gene
  3. Timp1 - tissue inhibitor of metalloproteinase 1 Gene

Timp1 - tissue inhibitor of metalloproteinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EPA; Clgi; Timp; TIMP-1; TPA-S1

Gene ID: 21857 | Gene type: protein coding

About Timp1

Summary

Predicted to enable several functions, including cytokine activity; metalloendopeptidase inhibitor activity; and zinc ion binding activity. Acts upstream of or within connective tissue replacement involved in inflammatory response wound healing. Located in basement membrane. Is expressed in several structures, including early conceptus; hindlimb cartilage condensation; jaw; reproductive system; and skeletal system. Orthologous to human TIMP1 (TIMP metallopeptidase inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Timp1 Products(3)

mRNA Protein Name
NM_001044384.1 NP_001037849.1 metalloproteinase inhibitor 1 isoform a precursor
NM_001294280.2 NP_001281209.1 metalloproteinase inhibitor 1 isoform b
NM_011593.2 NP_035723.2 metalloproteinase inhibitor 1 isoform a precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within connective tissue replacement involved in inflammatory response wound healing IDA
IDA: Inferred from direct assay
23100531 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
12950084 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
12950084 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metalloproteinase inhibitor 1

TPA-induced protein

collagenase inhibitor 16C8 fibroblast

erythroid-potentiating activity

tissue inhibitor of metalloproteinases 1

Recombinant Timp1 Proteins

Cat. No. Product Name Accession Purity
HY-P71110 TIMP-1 Protein, Mouse (HEK293) P12032 (C25-R205) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-47888 PLN-1474 Inhibitor 99.30% Unkown
HY-151932 FXR agonist 3 Agonist 95.94% Unkown
HY-147195 QH536 Inhibitor / Unkown
HY-162902 ALK5-IN-82 / Unkown
HY-RS14538 TIMP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Timp1 NCBI NCBI:7076