SLC16A9 - solute carrier family 16 member 9 Gene

Homo sapiens

Also known as MCT9; C10orf36

Gene ID: 220963 | Gene type: protein coding

About SLC16A9

Cytogenetic location: 10q21.2 Genomic coordinates (GRCh38): 10:59,650,764-59,710,079 (from NCBI)

This gene has 3 transcripts (splice variants), 275 orthologues and 13 paralogues. Biased expression in adrenal (RPKM 82.1), kidney (RPKM 62.2) and 9 other tissues.

Summary

Predicted to enable monocarboxylic acid transmembrane transporter activity. Involved in urate metabolic process. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC16A9 Products(6)

mRNA	Protein	Name
NM_001323977.1	NP_001310906.1	monocarboxylate transporter 9 isoform b
NM_001323978.2	NP_001310907.1	monocarboxylate transporter 9 isoform b
NM_001323979.2	NP_001310908.1	monocarboxylate transporter 9 isoform b
NM_001323980.2	NP_001310909.1	monocarboxylate transporter 9 isoform b
NM_001323981.2	NP_001310910.1	monocarboxylate transporter 9 isoform a
NM_194298.3	NP_919274.1	monocarboxylate transporter 9 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables carnitine transmembrane transporter activity	IDA IDA: Inferred from direct assay	21886157	GOA
enables creatine transmembrane transporter activity	IDA IDA: Inferred from direct assay	31784090	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in carnitine transmembrane transport	IDA IDA: Inferred from direct assay	21886157	GOA
involved in creatine transmembrane transport	IDA IDA: Inferred from direct assay	31784090	GOA
involved in urate metabolic process	IMP IMP: Inferred from mutant phenotype	19503597	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	31784090	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC16A9 Protein Structure

MFS_1

0
100
200
300
400
509 a.a.

Protein Preferred Names

Protein Names

monocarboxylate transporter 9

MCT 9

SLC16A9 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SLC16A9	Q7RTY1	MRPL11	Homo sapiens	Q9Y3B7	Y2H Array	25416956
Intra	SLC16A9	Q7RTY1	MRPL11	Homo sapiens	Q9Y3B7	Y2H Prey Pooling	25416956
Intra	SLC16A9	Q7RTY1	EIF4A2	Homo sapiens	Q14240	Y2H Array	25416956
Intra	SLC16A9	Q7RTY1	KLC4	Homo sapiens	Q9NSK0	Validated Y2H	25416956
Intra	SLC16A9	Q7RTY1	KLC4	Homo sapiens	Q9NSK0	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Gout

Gouty Arthritis	Articular Gout
Gouty Arthropathy	Arthritis, Gouty
Arthritis Gouty	Idiopathic Gout
Idiopathic Gout, Unspecified Site	Gouty Bursitis
Uratic Arthritis	Gout Nos
Gouty	Gouty Diathesis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13033	SLC16A9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SLC16A9	VGNC	VGNC:77564
Canis familiaris	SLC16A9	VGNC	VGNC:46247
Bos taurus	SLC16A9	VGNC	VGNC:34695
Mus musculus	SLC16A9	MGD	MGI:1914109
Felis catus	SLC16A9	VGNC	VGNC:65216
Rattus norvegicus	SLC16A9	RGD	RGD:1596295

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