2. Gene
  3. NT5DC1 - 5'-nucleotidase domain containing 1 Gene

NT5DC1 - 5'-nucleotidase domain containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as LP2642; NT5C2L1; C6orf200

Gene ID: 221294 | Gene type: protein coding

About NT5DC1

This gene has 4 transcripts (splice variants), 209 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 16.7), prostate (RPKM 14.4) and 25 other tissues.

Summary

While the exact function of the protein encoded by this gene is not known, it belongs to the 5'(3')-deoxyribonucleotidase family. [provided by RefSeq, May 2010]

NT5DC1 Products(1)

mRNA Protein Name
NM_152729.3 NP_689942.2 5'-nucleotidase domain-containing protein 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NT5DC1 Protein Structure

5_nucleotid

5_nucleotid: 5' nucleotidase family (4 - 341)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 455 a.a.
Protein Preferred Names Protein Names

5'-nucleotidase domain-containing protein 1

5'-nucleotidase, cytosolic II-like 1 protein

NT5DC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra NT5DC1 Q5TFE4 HSP90AA4P Homo sapiens Q58FG1
Anti Tag CoIP
33961781
Intra NT5DC1 Q5TFE4 HSP90AA4P Homo sapiens Q58FG1
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Metaphyseal Chondrodysplasia, Schmid Type

MCDS

Schmid Metaphyseal Chondrodysplasia

Metaphyseal Chondrodysplasia Schmid Type

Spondylometaphyseal Dysplasia, Japanese Type

Japanese Type Spondylometaphyseal Dysplasia

Schmid Type Metaphyseal Dysplasia

Metaphyseal Chondrodysplasia Type Schmid

Schmid Type Metaphyseal Chondrodysplasia

SMCD

Chondrodysplasia, Metaphyseal, Schmid Type

Corneal Dystrophy, Subepithelial Mucinous
Spastic Paraplegia 45, Autosomal Recessive

SPG45

Hereditary Spastic Paraplegia 45

Autosomal Recessive Spastic Paraplegia Type 45

Autosomal Recessive Spastic Paraplegia Type 65

Spg65

Autosomal Recessive Spastic Paraplegia 45

Paraplegia, Spastic, Type 45, Autosomal Recessive
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09610 NT5DC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NT5DC1 MGD MGI:2442446
Macaca mulatta NT5DC1 VGNC VGNC:81189
Rattus norvegicus NT5DC1 RGD RGD:1305214
Canis familiaris NT5DC1 VGNC VGNC:54336
Bos taurus NT5DC1 VGNC VGNC:32294
Felis catus NT5DC1 VGNC VGNC:63899