GSTA5 - glutathione S-transferase alpha 5 Gene

Homo sapiens

Gene ID: 221357 | Gene type: protein coding

About GSTA5

Cytogenetic location: 6p12.2 Genomic coordinates (GRCh38): 6:52,831,692-52,846,245 (from NCBI)

This gene has 2 transcripts (splice variants), 133 orthologues and 11 paralogues. Low expression observed in reference dataset.

Summary

The glutathione S-transferases (GST; EC 2.5.1.18) catalyze the conjugation of reduced glutathiones and a variety of electrophiles, including many known carcinogens and mutagens. The cytosolic GSTs belong to a large superfamily, with members located on different chromosomes. For additional information on GSTs, see GSTA1 (MIM 138359).[supplied by OMIM, Sep 2008]

GSTA5 Products(1)

mRNA	Protein	Name
NM_153699.2	NP_714543.1	glutathione S-transferase A5

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GSTA5 Protein Structure

GST_N

GST_C

0
100
200
222 a.a.

Protein Preferred Names

Protein Names

glutathione S-transferase A5

GST class-alpha member 5

GSTA5 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GSTA5	Q7RTV2	EIF3M	Homo sapiens	Q7L2H7	Anti Tag CoIP	33961781
Intra	GSTA5	Q7RTV2	TEX9	Homo sapiens	Q8N6V9	Y2H Prey Pooling	32296183
Intra	GSTA5	Q7RTV2	TEX9	Homo sapiens	Q8N6V9	Validated Y2H	32296183
Intra	GSTA5	Q7RTV2	TEX9	Homo sapiens	Q8N6V9	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05876	GSTA5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GSTA5	RGD	RGD:1593189

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