2. Gene
  3. Vcam1 - vascular cell adhesion molecule 1 Gene

Vcam1 - vascular cell adhesion molecule 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CD106; Vcam-1

Gene ID: 22329 | Gene type: protein coding

About Vcam1

Summary

Predicted to enable Integrin binding activity and primary amine oxidase activity. Acts upstream of or within several processes, including cellular response to glucose stimulus; chorio-allantoic fusion; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in apical plasma membrane. Is expressed in several structures, including brain; embryo mesenchyme; extraembryonic component; heart; and hemolymphoid system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human VCAM1 (vascular cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Vcam1 Products(1)

mRNA Protein Name
NM_011693.3 NP_035823.3 vascular cell adhesion protein 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell adhesion IDA
IDA: Inferred from direct assay
12021259 MGI
acts upstream of or within cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
17670746 MGI
acts upstream of or within chorio-allantoic fusion IMP
IMP: Inferred from mutant phenotype
7530222 MGI
acts upstream of or within embryonic placenta morphogenesis IMP
IMP: Inferred from mutant phenotype
7530222 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
7539357 MGI
acts upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
IMP: Inferred from mutant phenotype
8145052 MGI
acts upstream of or within leukocyte cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
8562500 MGI
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
30236446 MGI
located in cell periphery IDA
IDA: Inferred from direct assay
21464233 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vascular cell adhesion protein 1

V-CAM 1

Recombinant Vcam1 Proteins

Cat. No. Product Name Accession Purity
HY-P72432 VCAM-1/CD106 Protein, Mouse (HEK293, Fc) P29533 (F25-E698) ≥95%
HY-P73469 VCAM-1/CD106 Protein, Mouse (HEK293, His-Fc) Q3UPN1 (M1-E698) ≥95%
HY-P73470 VCAM-1/CD106 Protein, Mouse (HEK293, His) Q3UPN1 (F25-E698) ≥95%

Related Agents

Approval
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108831 Natalizumab Antagonist ≥99.10% Unkown
Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-108831A Natalizumab (Solution) Antagonist 98.72% Phase 4
Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0602 Ginsenoside Rg2 Inhibitor 98.11% Unkown
HY-W588250 Surfactin C1 Antagonist 99.36% Unkown
HY-N1990 Gypenoside XLIX Activator 99.15% Unkown
HY-N2110 Phellopterin 99.94% Unkown
HY-N0617 Sanggenon C 98.50% Unkown
HY-143243 Antioxidant agent-5 Inhibitor / Unkown
HY-14921 Elsibucol Inhibitor / Unkown
HY-159179 α4 integrin receptor antagonist 3 Inhibitor / Unkown
HY-N0602R Ginsenoside Rg2 (Standard) Inhibitor / Unkown
HY-N10047 7,8-Didehydrocimigenol Inhibitor / Unkown
HY-RS15618 VCAM1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-163712 17-Epiestriol Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vcam1 NCBI NCBI:7412