2. Gene
  3. Ybx1 - Y box protein 1 Gene

Ybx1 - Y box protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EF1A; MSY1; YB-1; dbpB; Nsep1; mYB-1a; 1700102N10Rik

Gene ID: 22608 | Gene type: protein coding

About Ybx1

Summary

Enables chromatin binding activity; mRNA binding activity; and single-stranded DNA binding activity. Involved in epidermis development and negative regulation of cellular senescence. Acts upstream of or within several processes, including cellular response to interleukin-7; negative regulation of striated muscle cell differentiation; and negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of histone pre-mRNA 3'end processing complex. Is expressed in several structures, including branchial arch; central nervous system; facial prominence; gonad; and retina. Orthologous to human YBX1 (Y-box binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ybx1 Products(1)

mRNA Protein Name
NM_011732.2 NP_035862.2 Y-box-binding protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
24788519 MGI
enables mRNA binding IDA
IDA: Inferred from direct assay
20713358 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8871564 MGI
enables single-stranded DNA binding IDA
IDA: Inferred from direct assay
15282343 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to interleukin-7 IDA
IDA: Inferred from direct assay
29581031 MGI
involved in epidermis development IMP
IMP: Inferred from mutant phenotype
29712925 MGI
acts upstream of or within in utero embryonic development IGI
IGI: Inferred from genetic interaction
16954378 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
16954378 MGI
involved in negative regulation of cellular senescence IMP
IMP: Inferred from mutant phenotype
29712925 MGI
acts upstream of or within negative regulation of striated muscle cell differentiation IDA
IDA: Inferred from direct assay
20004191 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
20004191 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
20004191 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
20713358 MGI
Cellular Component GO Annotation Evidence Reference Source
located in P-body IDA
IDA: Inferred from direct assay
20713358 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
20004191 MGI
part of histone pre-mRNA 3'end processing complex IDA
IDA: Inferred from direct assay
19470752 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20713358 MGI
located in nucleus IGI
IGI: Inferred from genetic interaction
20004191 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Y-box-binding protein 1

CBF-A

CCAAT-binding transcription factor I subunit A

DNA-binding protein B

EFI-A

Y-box transcription factor

enhancer factor I subunit A

nuclease-sensitive element-binding protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16252 Ybx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS15916 YBX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ybx1 NCBI NCBI:4904