2. Gene
  3. DNAJC8 - DnaJ heat shock protein family (Hsp40) member C8 Gene

DNAJC8 - DnaJ heat shock protein family (Hsp40) member C8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SPF31; HSPC331

Gene ID: 22826 | Gene type: protein coding

About DNAJC8

This gene has 6 transcripts (splice variants), 1 gene allele and 219 orthologues. Ubiquitous expression in lymph node (RPKM 41.4), endometrium (RPKM 36.7) and 25 other tissues.

Summary

Enables HSP70 protein binding activity. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DNAJC8 Products(1)

mRNA Protein Name
NM_014280.3 NP_055095.2 dnaJ homolog subfamily C member 8
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables Hsp70 protein binding IPI
IPI: Inferred from physical interaction
27133716 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
17332742 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
27133716 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DNAJC8 Protein Structure

DnaJ

DnaJ: DnaJ domain (57 - 117)

  • 0
  • 100
  • 200
  • 253 a.a.
Protein Preferred Names Protein Names

dnaJ homolog subfamily C member 8

DnaJ (Hsp40) homolog, subfamily C, member 8

DNAJC8 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
DNAJC8 O75937 SF3A2 Homo sapiens Q15428
Affinity Chrom
17332742
Intra
DNAJC8 O75937 AGTR1 Homo sapiens P30556
Ub Reconstruction
28298427
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03889 DNAJC8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DNAJC8 VGNC VGNC:80188
Mus musculus DNAJC8 MGD MGI:1915848
Canis familiaris DNAJC8 VGNC VGNC:52131
Bos taurus DNAJC8 VGNC VGNC:49059
Rattus norvegicus DNAJC8 RGD RGD:1306024